Irvin Modlin was born in
He subsequently studied gastrointestinal surgery,
endocrine surgery, and endoscopy at the
He is currently Professor of Surgery and Director of the Gastric Pathobiology Research Group at the Yale University School of Medicine.
In 1987, he was awarded an MA (Hon. Causa)
in literature by
Dr Modlin has delivered the Eisenberg Memorial lecture (Brigham and Women’s Hospital, 1993), the I. N. Marks lecture (Johannesburg, 1994), the Jena Poyla Memorial Lecture (Semmelweis University, Budapest, 1995), the Arris and Gale lecture (Royal Postgraduate Medical School, 1995), and the Theodor Kocher Oration (Bern, 1996). In 1997, the Royal College of Surgeons of England awarded Dr Modlin a Hunterian Professorship, and in 1998 a Fellowship. In 1999, he delivered the Bayliss and Starling Memorial Lecture at Queen’s University, Belfast, and in 2000 a Centenary Oration at the Japanese Surgical Society. In 2001 he presented a talk at the Nordic Endocrine Society Meeting, Iceland, and in 2002 the James IV Oration was delivered in Edinburgh, talks on stem cells (Japan Ulcer Research) and on integrated digestive surgery. In 2003, Dr Modlin delivered the Per Dubb Oration at the University of Gothenburg, Sweden, as well as endoscopic talks to the Royal Society of Medicine (London, England) and on GERD to the German Endoscopic Society as well as at the UEGW (Madrid, Spain).
Current research interests include the elucidation of the growth factor mediated transformation process of the enterochromaffin-like cell (ECL) and the development of intravenous receptor targeted isotopic neuroendocrine tumor irradiation. His recent books include: “Laparoscopic Surgery,” “From Prout to the Proton Pump,” “Acid Related Disease: Biology and Treatment,” “The History of Endoscopy,” “The Logic of Omeprazole,” “The History of Gastroenterology,” and “The Evolution of Therapy in Gastroenterology.” He has also written a series of medical travel and historical books on Rome (“From Galen to Glory”), Vienna (“From Billroth to Boas”), New Orleans (“Medicine on the Mississippi”), and Washingtonian medicine (“Medical Milestones on the Potomac”).
Dr Modlin’s initial interest in the gastrointestinal tract was stimulated by his fascination with the process of malo-lactic fermentation. His focus on endoscopy was prompted by an early paternal exposure to the art of cystoscopy. His subsequent involvement in the art and science of oenology and gastronomy amplified his focus on visceral matters and pepsis. Cognizant of Billroth’s admonition that “Only an individual familiar with the arts and science of the past is competent to define its progress in the future,” he has sought to interface a knowledge of current surgery and science with the lessons of antiquity. As an ardent member of the Beaumont, Prout, and Athenaeum Clubs, his interest in the historical and scientific aspects of medicine spans the Atlantic and its bordering continents.
Bibliography
II. Presentations
III. All Publications (N = 506)
A. Clinical (N = 153)
B. Research (N = 225)
C. Historical
Articles (N = 40)
D. Books (N = 17)
E. Book Chapters (N = 59)
F. Miscellaneous (N = 12)
Research Activities And
Interests
a) Scientific Research
Current research responsibility is as Director of the Gastric Pathobiology Research Group. This is a twenty to twenty-five member group variously studying pancreatic, gastric, ileal and colonic endocrine and biochemical phenomena in the gastrointestinal system. Persons involved are surgeons, PhDs, surgical residents, technicians and visiting scientists from different countries and institutions. The overall specific research areas are in brief as follows:
Pancreatitis:
Isolated pancreatic acini are utilized to provide a model for the study of intracellular zymogen activation. The methodology utilizes western blot techniques to identify active fragments. Immunogold electron microscopy is used to identify colocalization of enzymes in subcellular compartments.
Pepsinogen Secretion:
Isolated peptic cells are generated using elutriation centrifugation and nycodenz gradient systems. The mechanisms of exocytosis are studied with particular reference to identification of small GTP binding protein families and intracellular calcium flux. Characterization of CCK and gastrin type receptors is undertaken using peptide fragments and antagonists.
Parietal Cells:
Isolated parietal cells are studied with a view to identification of the subcellular mechanisms of secretion. This involves structural studies using confocal microscopy and biochemical cross-referencing using two dimensional gel separation of phosphorylated proteins. Specific identification of EGF and TGFa subcellular localization is the current primary goal.
Mastomys ECL Cells:
The histogenesis of the ECLoma tumor has been studied using cell culture and nude mice transfer. Western and northern blotting are used to demonstrate oncogene amplification. Secretion of tumor peptides and amines is assessed by HPLC and RIA methodology.
Intracellular pH Regulation:
The control of pH by specific related ion pumps is evaluated using isolated perfused gastric glands. This methodology involves fluorescent spectrophotometry and video enhanced isolated cell imagery. Calibration curves using Nigericin and cell loading with BCECF are components of the system.
b) Clinical Investigations
1. Minimally invasive surgery
2. Carcinoid tumors
3. Pancreatitis and neuroendocrine tumors of the pancreas
4. Peptic ulcer disease
c) Research Funding
|
Investigator |
Grant Title |
Agency |
Amount |
Dates |
|
I.M.
Modlin |
Secretagogue
Regulation of Protein Phosphorylation in Parietal Cells |
NIH |
$418,057 |
5/89-4/93 Complete |
|
J.R.
Goldenring (IMM
Co-Invest.) |
Cyclic
AMP-Dependent Mediation of Parietal Cell Function |
NIH |
$371,912 |
4/91-3/96 Complete |
|
I.M.
Modlin |
Pathophysiology
of an Endocrine Tumor - A Peptic Ulcer Model |
VA |
$490,000 |
10/88-9/96 Complete |
|
G.
Ballantyne (IMM
Co-Invest.) |
Release
of Peptide Tyrosine and Enteroglucagon from the colon |
VA |
$141,415 |
12/89-12/92 Complete |
|
M.
Basson (IMM
Co-Invest.) |
Growth
Factor - Matrix Interaction in the Regulation of Enterocyte Migration |
|
$7,000 |
12/90-11/91 Complete |
|
L.
Tang (IMM
Co-Invest.) |
Characterization
of a Tubulovesicle-Associated 23 kDa GTP-Binding Protein from Rabbit Parietal
Cell |
|
$9,000 |
12/90-11/91 Complete |
|
M.
Basson (IMM
Co-Invest.) |
Control
mechanisms for mammlian pepsinogen secretion |
NIH |
$35,300 |
7/91-6/92 Complete |
|
R.
Powers (IMM
Co-Invest.) |
Altered
acinar cell function during acute pancreatitis |
NIH |
$186,032 |
8/88-7/93 Complete |
|
I.M.
Modlin |
Research
Training in Surgical Gastroenterology |
NIH |
$705,190 |
7/91-6/96 Complete |
|
F.
Gorelick (IMM
Co-Invest.) |
Intracellular
Activation of Pancreatic Zymogens |
NIH |
$838,846 |
7/91-6/96 Complete |
|
C.
Soroka (IMM
Co-invest.) |
The
cultured parietal cell: a model for membrane-cytoskeletal interactions |
VA |
$288,900 |
4/92-3/95 Complete |
|
S.
Waisbren (IMM
Co-Invest.) |
Intracellular
pH regulation in perfused gastric glands |
NIH |
$29,500 |
7/91-6/92 Complete |
|
I.M.
Modlin |
Pathophysiology
of an Endocrine Tumor – Gastric ECLoma Model |
VA |
$450,000 |
9/96-8/00 Complete |
|
J.
Murren (IMM
Co-Invest) |
Isotopic
Therapy of SST expressing Neuroendocrine Tumors |
NCI |
$275,000 |
2/01-3/03 Active |
|
I.M.
Modlin |
Molecular
Strategies for Gastric Carcinoid Surgery |
NIH |
$650,000 |
8/03-7/05 Active |
|
I.M. Modlin |
Determination
of the naïve human EC cell transcriptome and identification of neoplastic
genes in a novel small intestinal carcinoid cell line |
Yale Univ |
$10,000 |
1/06-12/06 |
|
I.M. Modlin (Mark Kidd Co-Invest) |
Molecular strategies to
preemptively define gastrointestinal carcinoid surgery |
NIH |
$710,000 |
9/06-8/10 |
2006:
·
“Somatostatin
Radiopeptide Therapy”: American Society of Clinical Oncology,
·
“The Evolution of Acid Suppression”: Jan Mikulicz Memorial Meeting,
2005:
·
“Molecular
Genetics of Gastric Neoplasia”: Yokohama, Japan.
2004:
· “The Influence of Edinburgh on the founding of American Medical Schools”: American College of Surgeons/Royale College of Surgeons (Edinburgh).
·
“The Biology of Carcinoid Disease”:
European Neuroendocrine Tumor Society,
·
“The
Molecular basis of Carcinoid Fibrosis”: British Society of
Surgical Oncology,
·
“Evolution of GI disease
management”: American
2003:
·
“The Molecular Basis of the ECL cell”: Per Dubb Oration,
·
Current Status of GERD management. German
Endoscopic society,
·
“The
Evolution of Esophageal Therapy”: United European Gastroenterology
Weekly,
·
“From the Mucosa to the Serosa”:
Digestive Disease Weekly,
·
“From the Macula to the Mucosa”
Royal Society of Medicine,
·
Evolution of Pancreatic Therapy”
2002:
·
Invited speaker, “Cancer of Esophagus and
Gastric Cardia: From Gene to Cure,”
·
Invited speaker, “Perspectives and
reflections on integrated digestive surgery,” The Future of
Gastro-Entero-Hepato-Pancreatology is Bright,
·
Invited speaker, “
· Invited speaker, “Stem cells and mucosal dynamics: Regulation, repair and neoplasia,” Japanese Society of Ulcer Research
· Keynote address, Indian Hepatobiliary Society, “Surgery of chronic pancreatitis”
· James IV Oration, Edinburgh, “Molecular strategies and 111In-labeled somatostatin analogs in defining the management of neuroendocrine tumor disease: A new paradigm for surgical management”
·
External Surgical Assessor,
2001:
·
“Gastric Carcinoid Molecular
Biology,” Nordic Endocrine Society
· Controversies, Problems, and Techniques in Surgery Symposium
·
Invited Speaker International Pancreatic
Meeting,
2000:
1999:
·
The
· John Callum Memorial Oration
1998:
1)
MODLIN IM,
Moss SF, Oberg K, Padbury R, Hicks R, Gustafsson BI, Wright NA, Kidd M.
Gastrointestinal neuroendocrine (carcinoid) tumors – current diagnosis and
management. Australian Medical Journal 2010 (accepted).
2)
MODLIN IM,
Pavel M, Kidd M, Gustafsson BI. Somatostatin analogues: An appraisal of
their utility and efficacy. Aliment Pharmacol Ther (2009) (in press).
3)
Klimstra D,
MODLIN IM,
Adsay N, Chetty R, Deshpande V, Gonen M, Jensen R, Kidd M, Kulke M, R. L,
Moran C, Moss S, Oberg K, O’Toole D, Rindi G, Robert M, Suster S, Tang L,
Tzen C-Y, Washington M, Wiedenmann B, Yao J. Pathologic Reporting of
Neuroendocrine Tumors: Application of the Delphic Consensus Process to the
Development of a Minimum Pathologic Data Set. Am J Pathol (2009) (in press).
4)
MODLIN IM,
Wright NA, Gustafsson BI, Kidd M. Gastrointestinal neuroendocrine
(carcinoid) tumors. Gastroenterology (2009) (in press).
5)
Kahrilas PJ, Shaheen NJ, Vaezi MF, Hiltz SW, Black E,
MODLIN IM, Johnson SP, Allen J, Brill JV; American
Gastroenterological Association. American Gastroenterological Association
Medical Position Statement on the management of gastroesophageal reflux
disease. Gastroenterology. 2008
Oct;135(4):1383-1391, 1391.e1-5.
6)
MODLIN IM,
Hunt RH, Malfertheiner P, Moayyedi P, Quigley EM, Tytgat GN, Tack J,
Holtmann G, Moss SF. Non-erosive reflux disease--defining the entity and
delineating the management. Digestion.
2008;78 Suppl 1:1-5. Epub 2008 Oct 2.
7)
Pannala R, Kidd M,
MODLIN IM.
Acute pancreatitis: the rapid pace of no change. Pancreas 2009;38:355-66.
8)
MODLIN IM,
Moss SF, Chung DC, Jensen RT, Snyderwine E. Priorities for improving
management of gastropancreatic neuroendocrine tumors. J Natl Cancer Inst
2008; 100:1282-9.
9)
Gustafsson BI, Siddique Z-L, Chan AK, Manku D, Drozdov I, Kidd M,
MODLIN IM. Uncommon cancers of the small intestine, appendix and
colon: An analysis of SEER 1973-2004, and current diagnosis and therapy.
International Journal of Cancer 2008;
33:1121-31.
10)
MODLIN IM,
Kidd M, Drozdov I, Siddique Z-L, Gustafsson BI. Pharmacotherapy of
Neuroendocrine Cancers. Expert Opinion on Pharmacotherapy 2008; 9:2617-26.
11)
Hauso O, Gustafsson G, Kidd M, Waldum H, Drozdov I, Chan AK,
MODLIN IM. Neuroendocrine Tumor Epidemiology: Contrasting
12)
Gustafsson BI, Hauso O, Drozdov I, Kidd M,
MODLIN IM. Carcinoid Heart
Disease. (International Journal of Cardiology (2008) (in press).
13)
Bornschein J, Kidd M, Malfetheiner P,
MODLIN IM. Neuroendokrine
Tumoren des Gastrointestinaltraktes. Dtsch Med Wochenschr 2008;133:
1505-10.
14)
Gustafsson BI, Kidd M, Chan A,
Malfertheiner MV, MODLIN IM.
Bronchopulmonary neuroendocrine tumors. Cancer 2008; 113:5-21.
15)
MODLIN IM,
Moss SF. Symptom Evaluation in Gastroesophageal Reflux Disease. J Clin
Gastroenterol. 2008; 42:558-563.
16)
Hungin P, MODLIN IM. NERD: a new
approach in managing reflux symptoms. Fam Pract.
2008; 25:397-9.
17)
MODLIN IM,
Oberg K, Chung DC, Jensen RT, de Herder WW, Thakker RV, Caplin M, Delle Fave
G, Kaltsas GA, Krenning EP, Moss SF, Nilsson O, Rindi G, Salazar R,
Ruszniewski P, Sundin A. Gastroenteropancreatic Neuroendocrine Tumors.
Lancet Oncol 2008; 9:61-72.
18)
Gustafsson BI, Kidd M, MODLIN IM. Neuroendocrine tumors of the
Diffuse Neuroendocrine System. Current Opinion in Oncology 2008; 20:1-12.
19)
MODLIN IM,
Champaneria MC, Chan AKC, Kidd M. A three decade analysis of 3,911 small
intestinal carcinoids: The rapid pace of no progress. Am J Gastroenterol
2007; 102: 1464-73.
20)
Hunt RH, Tytgat G, Malfertheiner P, Fock KM, Heading R, Katelaris P,
McCarthy D, McColl KE, Moss SF, Sachs G, Sontag SJ, Thomson A, MODLIN IM. Whistler Summary: “the slow rate of progress”. J. Clin
Gastroenterol 2007; 41:539-45.
21)
Moss SF, Kidd M, MODLIN IM. The
status of the hiatus: the role of hernia in gastroesophageal reflux disease.
J Clin Gastroenterol (2007) (in press).
22)
Hunt RH, Malfertheiner P, Armstrong D, Holtmann G, Quigley EMM, Spechler SJ,
MODLIN IM. GERD Evaluation – Time
for a new paradigm. J Clin Gastroenterol 2007; 41:237-41.
23)
Pannala R, Gafni-Kane A, Kidd M,
MODLIN IM. An Ileal Endometrioma: Of Carcinoids and Cadherin.
J Gastrointestinal Surgery 2007; 11:229-32.
24)
MODLIN IM,
Shapiro MD, Kidd M. Primary carcinoid tumor of the parotid: a case report
and review of the literature. Ear Nose Throat Journal 2006; 85:533-9.
25)
Latich I, MODLIN IM, Zikusoka MN,
Kidd M, Eick G, Chan A.
Gastrointestinal carcinoids – the Evolution of Diagnostic strategies. J Clin
Gastroenterol 2006; 40:572-82.
26)
MODLIN IM, Latich I,
Kidd M,
27)
Pannala R, Kidd M, MODLIN IM.
Surgery for the Obese: A Panacea? Digestive Surgery 2006; 23:1-11.
28)
Malfertheiner P,
Fass R,
Quigley EM,
MODLIN IM,
Malagelada JR, Moss SF,
Holtmann G,
Goh KL,
Katelaris P, Stanghellini V,
Talley NJ,
Tytgat GN,
Wright NA. Review article:
from gastrin to gastro-oesophageal reflux disease--a century of acid
suppression.
Aliment Pharmacol Ther. 2006 Mar 15;23(6):683-90
29)
Ballantyne GH, Gumbs A,
MODLIN IM. Changes in insulin resistance following bariatric
surgery and the adipoinsular axis: role of the adipocytokines, leptin,
adiponectin and resistin.
Obes Surg. 2005 May;15(5):692-9.
30)
Gumbs AA,
MODLIN IM, Ballantyne GH. Changes in insulin resistance
following bariatric surgery: role of caloric restriction and weight loss.
Obes Surg. 2005 Apr;15(4):462-73.
31)
MODLIN IM,
Adler G, Alexander K, Arnold R, Brenner DA, Corazziari E, Floch MH, LaPorte
RE, Peterson WL, Quigley EM, Shapiro MD, Spechler SJ, Spiller RC, Tytgat GN,
Wiegers W. Information assimilation and distribution challenges and goals
for real and virtual journals. J Clin Gastroenterol. 2005; 39: 181-8.
32)
MODLIN IM,
Kidd M, Latich I,
33)
Buragas M, Kidd M, MODLIN IM, Cha
C. Multiple gastrointestinal stromal tumors and synchronous ileal carcinoid.
Nature Medicine Clinical Practice 2005; 2(3): 1-5.
34)
MODLIN IM,
Shapiro MD, Kidd M. A Miscellany of rare carcinoids – Clarifying the
clinical conundrum. World J. Surg 2005; 29:92-101.
35)
MODLIN IM,
Shapiro MD, Kidd M. Carcinoid tumors and fibrosis: a relation with little
explanation. Am J Gastro 2004; 99:2466-2478.
36)
MODLIN IM,
Kidd M. GERD 2003: Issues from the past and a consensus for the future. Best
Practice & Research Clinical Gastroenterology 2004; 18 Suppl: 55-66.
37)
Mullerpatan PM, Joshi SR, Shah RC, Tampi CS, Doctor VM, Jagannath P,
MODLIN IM. Calcitonin-secreting tumor of the pancreas. Dig Surg
2004; 21:321-324.
38)
Abir F, MODLIN IM, Kidd M,
39)
MODLIN IM,
Moss SF, M Kidd, K Lye. Gastro-Esophageal Reflux Disease - Then and Now. J
Clin Gastroenterol, 2004; 38:390-402.
40)
MODLIN IM,
Kidd M. GERD 2003: Issues from the past and a consensus for the future.
Drugs Today 2004; 40(Suppl 1A) 3-8.
41)
MODLIN IM,
Lye K, Kidd M. Multiple gastric carcinoids. J Am Coll Surg 2004; 198: 174.
42)
MODLIN IM,
Lye K, Kidd M. A 50-year analysis of 562 gastric carcinoids: small tumor –
or larger problem? Am J Gastroenterol 2004; 99: 23-32.
43)
Koelz HR, Blum
44)
MODLIN IM, Kidd M, Lye K. Carcinoid
Tumors of the Stomach. Surgical Oncology 2003; 12:153-172.
45)
Moss SF, Armstrong D, Arnold R, Ferenci P, Fock KM, Holtmann G, McCarthy DM,
Moraes-Filho JP, Mutschler E, Playford R, Spechler SJ, Stanghellini V,
MODLIN IM.
GERD 2003 - A Consensus on
the Way Ahead.
Digestion. 2003;67(3):111-7.
46)
MODLIN IM, Kidd M, Lye KD, Murren
J, Argiris A. Molecular Strategies and 111In-labeled somatostatin analogues
in defining the management of neuroendocrine tumour disease: a new paradigm
for surgical management. The Surgeon 2003; 1(3): 137-143.
47)
MODLIN IM, Lye KD, Kidd M. A
5-decade analysis of 13,715 carcinoid tumors. Cancer 2003; 97:934-959.
48)
Gumbs AA, Moore PS, Falconi M, Bassi C, Beghelli S, MODLIN IM, Scarpa
A. Review of the clinical, histological, and molecular aspects of pancreatic
endocrine neoplasms. J Surg Oncol. 2002; 81:45-53.
49)
Moss SF, MODLIN IM. Summation: irritable bowel and the irritable
physician. J Clin Gastroenterol. 2002; 35 (1 Suppl):S68-70.
50)
MODLIN IM. Efficacy and safety of intravenously administered
pantoprazole in the treatment of gastrinoma. Recenti Prog Med 2001;
92:456-461.
51)
Lew EA, Pisegna JR, Starr JA,
Soffer EF, Forsmark C, MODLIN IM, Walsh JH, Beg M, Bochenek W, Metz
DC. Intravenous pantoprazole rapidly controls gastric acid hypersecretion in
patients with Zollinger-Ellison syndrome. Gastroenterol 2000; 118:696-704.
52)
53)
MODLIN IM,
Tang LH. Cell and tumour biology of the gastric enterochromaffin-like cell.
Ital J Gastroenterol Hepato 1999:31(supp2):S117-30.
54)
MODLIN IM,
Tang LH, Svennevik. Gastric Carcinoid Tumors. Surgical Endocrinology, 2001,
30:431-446.
55)
Schonfeld WH, Eiken EP,
Woltering EA, MODLIN IM, Anthony
L, Villa KF, Zagari M. The cost-effectiveness of octreotide acetate in the
treatment of carcinoid syndrome and VIPoma. Int J Technol Assess Health Care
1998; 14:514-525
56)
Sandor A,
MODLIN IM. A retrospective analysis of 1570 appendiceal carcinoids.
Am J Gastreoterol 1998; 93:422-428
57)
Moss SF, Fendrick AM,
58)
MODLIN IM,
Sandor A, Tang LH, Kidd M, Zelterman D. A 40 year analysis of 265 gastric
carcinoids. Am J Gastroenterol 1997; 92: 633-638
59)
Begos DG, Sandor A,
MODLIN IM. The Diagnosis and
Management of Adult Intussusception. Am J Surg 1997, 173: 88-94
60)
MODLIN IM,
Tang LH. Approaches to the diagnosis of Gut neuroendocrine tumors: The last
word (Today). Gastroenterol 1997, 112: 583-590
61)
MODLIN IM,
Sandor A. An analysis of 8305 Cases of Carcinoid Tumors. Cancer 1997,
79:813-829
62)
MODLIN IM,
Gilligan CJ, Lawton GP, Tang LH, West AB, Lindenberg R. Observations on
relationship between hypergastrinemia, multiple gastric carcinoids, and
pancreatic mass. Dig Dis Sci 1996; 41(1):105.14.
63)
MODLIN IM,
64)
MODLIN IM,
Gilligan CJ,
65)
MODLIN IM.
To Repair the Fault or End the Acid Reign? Scand J Gastroenterol 1995; 30
Suppl 210:1-5.
66)
MODLIN IM
and Hunt RH. Critical Reappraisal of Mucosal Repair Mechanisms. Scand J
Gastroenterol 1995; 30 Suppl 210: 28-31.
67)
Begos DG, Franco KL, Baldwin
JC, Lee FA, Revkin JH, MODLIN IM.
Optimal Timing And Indications For Cholecystectomy In Cardiac Transplant
Patients. World J Surg. 19, 661-667, 1995.
68)
Gilligan CJ, Tang LH,
69)
Sgambati SA,
70)
Begos DG,
MODLIN IM. Laparoscopic Cholecystectomy: From Gimmick To Gold
Standard. J Clin Gastroenterol 1994; 19(4):325-30.
71)
MODLIN IM,
72)
Mani S,
MODLIN IM, Ballantyne G, Ahlman H, West B. Carcinoids of the Rectum.
Jo Am Coll Surg 1994, 179; 231-248.
73)
MODLIN IM,
74)
75)
Ginsberg RJ, Miller TA,
MODLIN IM. Esophageal, gastric
and small intestine (editorial overview). In: Current Opinion in General
Surgery 1994: 109-112, ed JM Daly, Current Science.
76)
MODLIN IM,
Goldenring JR,
77)
Basis and Clinical Relevance
of Low Acid States. Am J Gastro 1994;89(3):308-18.
78)
Begos DG,
MODLIN IM. Editorial: Gastrin and
79)
80)
MODLIN IM,
Lewis JL, Kumar RR, Bilchik AJ, Ahlman H. Management of unresectable
malignant endocrine tumors of the pancreas. Surg Gynecol Obstet 1993;
176:507-518.
81)
Basson MD, Ahlman H, Wangberg
B, MODLIN IM. Biology and
management of the midgut carcinoid. Am J Surg 1993; 165:288-297.
82)
83)
MODLIN IM,
Stoch SA, Soybel DI, Nilsson A, Ahlman H. Biological markers of
neuroendocrine tumors of the gastrointestinal tract and pancreas. Eur J Surg
1992; 157:629-645.
84)
Havlik RJ, Fried I, Chyatte D,
MODLIN IM. Encephalo-Omental
synangiosis in the management of moyamoya disease. Surgery 1992;
111(2):156-162.
85)
Yapp R, MODLIN IM, Kumar RR,
Binder HJ, Dubrow R. Gastrin and colorectal cancer: evidence against an
association. Dig Dis and Sci 1992; 37(4):481-484.
86)
MODLIN IM.
Adaptation and renewal of the gastrointestinal surgeon to meet the
continuous challenge of modern gastroenterology. Scand J Gastroenterol 1992;
27(Suppl 193):100-105.
87)
Haque S,
MODLIN IM, West AB. Multiple Glomus Tumors of the Stomach With
Intravascular Spread. Am J of Surg Pathol 16(3): 291-299, 1992.
88)
89)
Basson MD,
MODLIN IM, Flynn SD. Gastric stromal tumors: current clinical and
pathological perspectives. Surg, Gynecol and Obstet 1992; 175(5):477-89.
90)
Lewis J, Basson M,
MODLIN IM. Surgical therapy in acute esophageal variceal hemorrhage.
Dig Dis . Scarpignato C, MODLIN IM
(Ed) Karger 1992; 10 (1):46-55.
91)
Scarpignato C,
MODLIN IM (eds). The management of esophageal varices: In Digestive
Dis Suppl. Karger 1992; 10(1):1-2.
92)
Soybel DI,
MODLIN IM. Implications of sustained suppression of gastric acid
secretion. Am J Surg 1992 June; 163(6):613-622.
93)
Ahlman H, Wangberg B, Nilsson
O, Grimelius L, Granerus G, MODLIN IM,
Stenovist O, Schersten T. Aspects on diagnosis and treatment of the foregut
carcinoid syndrome. Scand J Gastro 1992; 27:459-471.
94)
Soybel DI,
MODLIN IM. Sustained suppression of gastric secretion and the risk
of neoplasia in the gastric mucosa. Am J Gastro 1991; 86(12):1713-1719.
95)
Ballantyne GH, Savoca PE,
Flannery JT, Ahlman H, MODLIN IM.
Incidence and mortality of carcinoids of the colon: Data from the
Connecticut Tumor Resistery. Cancer 1992; 69(10):2400-2405.
96)
97)
Berkowitz I, Marks IN,
MODLIN IM. Case report. Low acid,
high gastrin-a signal sequence for gastric endocrine neoplasia? Eur J Gastro
& Hepat 1991; 3:198-91.
98)
99)
Armstrong DN, Ballantyne GH,
MODLIN IM. Erythromycin for
reflex ileus in Ogilvie's syndrome. Lancet 1991; 337:338.
100)
Ballantyne GH,
101)
102)
103)
Brophy CM, Ballantyne GH,
MODLIN IM. Small bowel
obstruction secondary to phytobezoar in the post gastrectomy patient.
Contemp Surg 1990; 37:27-33.
104)
Vukasin AP, Ballantyne GH,
Flannery JH, Lerner E, MODLIN IM.
Increasing incidence of cecal and sigmoid carcinoma: data from the
105)
106)
Reilly JM, Ballantyne GH, Zdon
MJ, Zucker KA, MODLIN IM.
Evlauation of the occult blood test in screening for colorectal neoplasms: a
prospective study utilizing flexible endoscopy. Am Surgeon 1990; 56:119-123.
107)
Longo WE, Ballantyne GH,
MODLIN IM. Colorectal disease in
spinal cord patients: an occult diagnosis. Disease of the Colon & Rectum
1990; 33(2):131-134.
108)
109)
Leach S, Gorelick F,
MODLIN IM. Acute Pancreatitis at
Its Centenary: The Contribution of Reginald Fitz. Ann Surg 1990;
212(1):109-113.
110)
Tierney R, Ballantyne G,
MODLIN IM. The Adenoma to
Carcinoma Sequence. Surg Gynecol & Obstet 1990; 171(1):81-94.
111)
Bilchik A, Leach S, Zucker K,
MODLIN IM. Experimental Models of
Acute Pancreatitis. J Surg Research 1990; 48:639-647.
112)
Wong TY, Enriquez RE,
MODLIN IM, Soldano L, Ouellette
GS, Kapadia CR. Recurrent Hemorrhage from an invaginated Meckel's
diverticulum in a 78-year-old man. Am J or Gastroenterology 1990; 85:2.
113)
Zucker ZA, Longo WE,
MODLIN IM, Bilchik AJ,
114)
Longo WE, Baker CB, McMillen
MA, MODLIN IM, Degutis LC, Zucker
KA. Nonoperative management of adult blunt splenic trauma: Criteria for
successful outcome. Ann Surg 1989; 210(5):626-629.
115)
Longo WE, Zucker KA, Zdon MJ,
MODLIN IM. Detection of early
gastric cancer in an aggressive endoscopy unit. Am Surg 1989; 55
(2):100-104.
116)
Longo WE, Ballantyne GH,
MODLIN IM. The colon, anorectum
and spinal cord patient. A review of the functional alterations of the
denervated hindgut. Dis Col & Rect 1989; 32(3):261-267.
117)
Brophy CM, Morris J, Sussman
J, MODLIN IM. "Pseudoascites"
secondary to an amylase-producing serous ovarian cystadenoma. J Clin
Gastroenterol 1989; 11(6):703-706.
118)
Ballantyne GH,
MODLIN IM. Postoperative follow-up for colorectal cancer: Who are we
kidding? J Clin Gastro 1988; 10(4):359-364.
119)
Romano TJ, Graham SM, Chuong
J, Ballantyne GH, MODLIN IM,
Sussman J, West AB. Bleeding colonic ulcers secondary to atheromatous
microemboli after left heart catheterization. J Clin Gastro 1988;
10(6):693-698.
120)
Longo WE, Ballantyne GH,
Bilchik AJ, MODLIN IM. Advanced
rectal cancer. What is the best palliation? Dis
121)
Longo WE, Ballantyne GH,
MODLIN IM. Colonoscopic detection
of early colorectal cancers: Impact of a surgical endoscopy service. Ann
Surg 1988; 207: 174-178.
122)
Longo WE, Zucker KA, Zdon MJ,
MODLIN IM. Gastric cancer in
123)
Rubin BG, Ballantyne GH, Zdon
MJ, Zucker KA, MODLIN IM. The
role of flexible sigmoidoscopy in the preoperative screening of patients
with inguinal hernia. A high yield of neoplasms. Arch Surg 1987;
122:296-299.
124)
Letsou G, Ballantyne GH, Zdon
MJ, Zucker KA, MODLIN IM.
Screening for colorectal neoplasms: A comparison of the fecal occult blood
test and endoscopic examination. Dis
125)
126)
Longo WE, Zucker KA, Zdon MJ,
Ballantyne GH,
127)
Graham SM, Ballantyne GH,
MODLIN IM. Gastric epithelioid
leiomyomatous tumors: Review of the literature. Surg Gynecol Obstet 1987;
164:391-397.
128)
Graham SM, Ballantyne GH,
MODLIN IM. Gastric epithelioid
leiomyosarcoma: A curable gastric neoplasm. Am J Gastroenterol 1987;
82:82-85.
129)
Basson MD,
MODLIN IM. Pepsinogen: Prolate ellipsoid or unrecognized pathogen? J
Clin Gastroenterol 1987; 9(4): 75-479.
130)
Ballantyne GH, Graham S,
Hammers L, MODLIN IM. Superior
mesenteric artery syndrome following ileal “J”-pouch anal anastomosis: An
iatrogenic cause of early postoperative obstruction. Dis
131)
Ballantyne GH,
MODLIN IM. Advances of endoscopic therapy for gastric diseases.
Problems in Gen Surg 1987; 4: 223-238.
132)
Sumpio BE, Ballantyne GH, Zdon
MJ, MODLIN IM. Perforated
appendicitis and obstructing colonic carcinoma in the elderly. Dis
133)
Longo WE, Ballantyne GH,
Gerald WL, MODLIN IM. Squamous
cell carcinoma in situ in condyloma accuminatum. Dis
134)
Letsou G, Ballantyne GH, Zdon
MJ, MODLIN IM. Rectal carcinoma
in a renal transplant patient. Long term complication of immunosuppression?
Dis
135)
Peterson JM, McCallum RW,
Gartman D, MODLIN IM. The medical
and surgical approach to gastroesophageal reflux. Pract Gastroenterol 1985.
136)
Letsou G, Ross P, Ballantyne
GH, Zdon MJ, MODLIN IM. Flexible
sigmoidoscopy versus stool guaiac as a screening test for lesions of the
distal colon and rectum. Gastrointest Endosc 1985; 31(2):148.
137)
MODLIN IM,
Brennan MF. The diagnosis and management of gastrinoma. Surg Gynecol Obstet
1984; 158(1):97-104.
138)
MODLIN IM,
Jaffe BM, Sand A, Albert D. The early diagnosis of gastrinoma. Ann Surg
1982; 196(5): 512-517.
139)
MODLIN IM.
Carcinoid syndrome. J Clin Gastroenterol 1980; 2(4):349-354.
140)
MODLIN IM.
Endocrine tumors of the pancreas. Surg Gynecol Obstet 1979; 149(II):751-769.
141)
MODLIN IM,
Lamers CBH. Multiple endocrine neoplasia type II (Sipple's Syndrome).
142)
MODLIN IM,
Lamers CBH. Multiple endocrine neoplasia type I (Wermer's Syndrome).
143)
MODLIN IM,
Farndon JR, Sheperd A, Johnston IDA, Kennedy TL,
144)
MODLIN IM,
Bloom SR, Mitchell S. VIP: the cause of the watery diarrhea syndrome. Adv
Exp Med Biol 1978; (106):195-201.
145)
Maempel FZ,
MODLIN IM,. Diagnosis and management of gastric carcinoid tumours
with hepatic metastases. Br J Surg 1978; 65(7):516-520.
146)
Tarin D, Allison DJ,
MODLIN IM, Neale G. Diagnosis and
management of obscure gastrointestinal bleeding. Br Med J 1978 Sep; 2:
751-755.
147)
MODLIN IM,
Spencer J. Unilateral short thumb associated with bleeding duodenal
reduplication. Br Med J 1978; 1(6110):412.
148)
MODLIN IM,
Bloom SR. VIPomas and the watery diarrhoea syndrome.
149)
MODLIN IM,
Bloom SR, Barnes A, Welbourn RB. Cure of intractable watery diarrhoea by
excision of a vipoma. Br J Surg 1978; 65(4):234-236.
150)
Allison DJ,
MODLIN IM, Jenkins WJ. Treatment of carcinoid liver metastases by
hepatic-artery embolization. Lancet 1977 Dec; 2(8052-8053):1323-1325.
151)
MODLIN IM,
Christofides N, Bloom SR. Plasma-motilin and carcinoid tumors. Lancet 1977,
Nov; 2(8045):979.
152)
McCloy RF,
MODLIN IM. Cimetidine, pH and the Zollinger-Ellison Syndrome. Lancet
1977; 2(8048):1131-1132.
153)
MODLIN IM,
Bloom SR. Overdiagnosis of endocrine gut tumors. Lancet 1977 Jun; 1:1366.
Return to Publications Index
1)
Kidd M, Siddique Z-L, Drozdov I, Gustafsson BI, Camp RL, Black JW, Boyce M,
MODLIN IM. The CCK2 receptor
antagonist, YF476, inhibits Mastomys
ECL cell hyperplasia and gastric carcinoid tumor development. Regulatory
Peptides 2010 (in press).
2)
Svejda B, Kidd M, Giovinazzo F, Eltawil K, Gustafsson BI, Pfragner R,
MODLIN IM. The 5-HT2B
receptor plays a key regulatory role in both neuroendocrine tumor cell
proliferation and the modulation of the fibroblast component of the
neoplastic microenvironment. Cancer (2010) (in press).
3)
Drozdov I, Kidd M, Gustafsson
BI, Joseph R, Pfragner R, MODLIN IM.
The Auto-regulatory Effect of Serotonin on the Proliferation and Associated
Signaling Pathway of Lung and Small Intestine Neuroendocrine Cell Lines
Cancer (2009) (in press).
4)
Kidd M, Hauso Ø, Drozdov I, Gustafsson BI,
MODLIN IM. Delineation of the
chemomechanosensory regulation of gastrin secretion using pure rodent G
cells. Gastroenterology 2009 (e_Pub Jan 14).
5)
Drozdov I, Kidd M, Nadler B, Camp R, Mane M, Gustafsson BI, Hauso O,
MODLIN IM. Predicting
Enterochromaffin Cell Neoplasia Using Gene Expression Profiling and
Supervised Machine Learning. Cancer 2009; 115:1638-50.
6)
MODLIN IM,
Gustafsson BI, Drozdov I, Kidd M. Principal Component Analysis, Hierarchical
Clustering, and Decision Tree Assessment of Plasma mRNA and Hormone Levels
as an Early Detection Strategy for Small Intestinal Neuroendocrine
(Carcinoid) Tumors. Annals Surgical Oncology (2008) (Dec 3_ePub).
7)
Kidd M, Gustafsson BI, Drozdov
I, MODLIN IM. Serotonin secretion
from Crohn’s disease EC cells is increased and mediated by IL1 and LPS
through TOLL receptor 4 (TLR4) activation of
NFκ. Neurogastroenterology &
Motility (2008) (Oct 25_ePub).
8)
Siddique Z-L, Drozdov I, Floch J, Gustafsson BI, Stunes K, Pfragner R, Kidd
M, MODLIN IM. KRJ-I and BON cell
lines: defining an appropriate enterochromaffin cell neuroendocrine tumor
model. Neuroendocrinology (2009) (e_Pub Mar 18).
9)
Kidd M,
MODLIN IM, Gustafsson BI, Drozdov
I, Hauso O. Luminal regulation of normal and neoplastic human EC cell
serotonin release is mediated by bile salts, amines, tastants, and
olfactants. Am J Physiol 2008; 295:G260-72.
10)
Kidd M, Drozdov I, Joseph R, Pfragner R, Culler M,
MODLIN IM. Differential cytotoxicity of novel somatostatin and
dopamine chimeric compounds on bronchopulmonary and small intestinal
neuroendocrine tumor cell lines. 2008; 113:690-700.
11)
Bornschein J, Kidd M, Eick
GN, Pfragner R, MODLIN IM.
Systematic Cytotoxic Analysis of Common Chemotherapeutic Agents On Lung and
Small intestinal Carcinoid Cell lines. J Cancer Molecules 2008; 4: 47-54.
12)
Kidd M, Schally AV, Pfragner R,
Malfertheiner MV, MODLIN IM.
Inhibition of Proliferation of Small Intestinal and Bronchopulmonary cell
lines using analogues targeting receptors. Cancer 2008; 112:1404-14.
13)
Sachs G, Shin JM, Munson K, Vagin O,
Kidd M, MODLIN IM. Molecular
Mechanisms in Therapy of Acid Related Diseases. Cellular and
Molecular Life Sciences 2008; 65:264-81.
14)
Kidd M,
Nadler B, Mane SM, Eick GN, Champaneria MC, Pfragner R,
MODLIN IM.
GeneChip, geNorm and GI carcinoids: novel reference genes for real-time PCR.
Physiological Genomics 2007; 30: 363-70.
15)
Kidd M,
MODLIN IM, Pfragner R, Eick GN,
Champaneria MC, Chan AO, Camp RL, Mane SM.
Small bowel Carcinoid (EC cell) Neoplasia exhibits TGF
b1-Mediated
regulatory abnormalities including Up-regulation of C-Myc and MTA1 Cancer
2007; 109: 2420-31.
16)
Kidd M, MODLIN IM,
Shapiro MD, Camp RL, Mane SM, Lye KD, Usinger W, Murren J. CTGF, intestinal
stellate cells and carcinoid tumor fibrogenesis. World Journal of
Gastroenterology 2007; 13:5208-16.
17)
Kidd M,
MODLIN IM, Black JW, Boyce M,
Culler M.
Examination of novel gastrin, somatostatin and dopamine receptor compounds
on gastric enterochromaffin-like cell function. Regulatory Peptides
2007; 143:109-17.
18)
Kidd M, MODLIN IM, Eick GN, Camp RL, Mane SM. The role of
CCN2/CTGF in the proliferation of
Mastomys ECL cells and gastric
carcinoid development. Am J Physiol
2007 Jan;292(1):G191-200.
19)
Kidd M, Eick GN, Mane SM, Nadler B, Champaneria MC, Pfragner R, MODLIN IM.
Further delineation of the continuous human neoplastic enterochromaffin cell
line, KRJ-I, and the inhibitory effects of lanreotide and rapamycin. J Mol
Endocrinol. 2007; 38:181-92.
20)
MODLIN IM,
Kidd M, Pfragner R, Eick GN,
Champaneria MC. The Functional Characterization of Normal and Neoplastic
Human Enterochromaffin Cells. J Clinical Endocrinology and Metabolism 2006;
91:2340-8.
21)
Kidd M,
MODLIN IM, Eick GN, Champaneria
MC. Isolation, Functional Characterization and Transcriptome of Mastomys
Ileal Enterochromaffin Cells. Am J Physiol 2006 Nov;291(5):G778-91.
22)
Kidd M, MODLIN IM, Shapiro MD,
Camp RL, Mane SM, Lye KD, Usinger W, Murren J.
CTGF, intestinal stellate cells and
carcinoid tumor fibrogenesis. World J Gastro (2006) (in press).
23)
Kidd M, MODLIN IM, Mane SM, Camp
RL, Latic I,
24)
MODLIN IM, Kidd M,
Latich I, Zikusoka MN, Eick G, Mane
SM, Camp RL. Genetic differentiation of appendiceal carcinoid malignancy – a
guide for the perplexed. Annals of Surgery 2006; 244:52-60.
25)
Kidd M, MODLIN IM, Mane SM,
26)
Kidd M, MODLIN IM, Mane SM, Camp
RL, Eick G, Latich I. The role of genetic markers, NAP1L1, MAGE-D2 and MTA1,
in defining small intestinal carcinoid neoplasia. Annals of Surgical
Oncology 2006; 13:253-62.
27)
28)
Shen
Z, Xu S, Dewhirst FE, Paster BJ, Pena JA, Kidd M,
MODLIN IM, Fox JG.
A Novel Enterohepatic Helicobacter
sp. H. natalensis Isolated from the Liver and Intestine of Rodents.
Helicobacter 2005; 10: 59-70.
29)
Kidd M, Eick G, Shapiro MD, Camp RL, Mane SM,
MODLIN IM.
Microsatellite instability and
gene mutations in TGFbRII are absent in small bowel carcinoids. Cancer
2005, 103:229-36.
30)
Kidd M, Hinoue T, Eick G, Lye
KD, Wei Y, Mane SM,
MODLIN IM. Global gene expression analysis of
enterochromaffin-like cells in the Mastomys gastric mucosa identifies
alterations in the activator protein-1 pathway. Physiol Genomics 2004;
20:131-142.
31)
MODLIN IM, Kidd M, Lye KD, Wright
NA.
Gastric stem cells: an update.
Keio J Med. 2003 Jun;52(2):134-7.
32)
Stalberg P, Granberg D, Carling T, Wilander E, Eriksson B, Gobl A, Akerstrom
G, Rastad J, MODLIN IM, Oberg K, Skogseid B.
In situ RNA-RNA hybridisation of phospholipase C beta 3 shows lack of
expression in neuroendocrine tumours.
Anticancer Res. 2003; 23(3B):2227-32.
33)
Saikawa Y, Kubota T, Otani Y, Kitajima M, MODLIN IM.
Alteration of DNA methylation status induced by epidermal growth factor in
gastric cancer cell line, MKN-74.
Anticancer Res. 2003 Jan-Feb;23(1A):143-8.
34)
Modlin IM, Kidd M. Case study: Ranitidine/Loxtidine in
“Predictive value of rodent forestomach and gastric neuroendocrine tumors in
evaluating carcinogenic risk to humans”. IARC Technical Publication No. 39
(2003):167-176.
35)
Modlin IM, Kidd M.
Praomys (Mastomys) natalensis as a model for gastric carcinoids in
“Predictive value of rodent forestomach and gastric neuroendocrine tumors in
evaluating carcinogenic risk to humans” IARC Technical Publication No. 39
(2003):109-119, 2003.
36)
Gumbs AA, Bassi C, Moore PS, Falconi M, Frigerio I, Baron A, Piemonti L,
MODLIN IM, Scarpa A.
Overexpression of the
Sm-Like Proto-Oncogene in Primary and Metastatic Pancreatic Endocrine
Tumors.
JOP. J Pancreas (Online) 2002; 3:109-115.
37)
Young GO, Brown S, Stemmet N,
Lastovica AJ, Louw JA, Marks IN, MODLIN IM, Kidd M. The pepsinogen
releasing effect of Helicobacter pylori lipopolysaccharide.
Helicobacter 2002 7:30-38.
38)
Lauffer JM, Tang LH, Zhang T,
Hinoue T, Rahbar S, Odo M, MODLIN IM,
Kidd M. PACAP mediates the
neural proliferative pathway of Mastomys Enterochromaffin-like cell
transformation. Regulatory Peptides 2001; 102:157-164.
39)
Saikawa Y, Kubota T, Otani Y, Kitajima M, MODLIN IM.
Cyclin D1 antisense
oligonucleotide inhibits cell growth stimulated by epidermal growth factor
and induces apoptosis of gastric cancer cells. Jpn J Cancer Res 2001;
92:1102-1109.
40)
Peek
RM, Wirth HP, Moss SF, Yang M, Abdalla AM, Tham KT, Zhang T, Tang LH,
MODLIN IM, Blaser MJ.
Helicobacter pylori alters gastric epithelial cell cycle events and
gastrin secretion in Mongolian gerbils. Gastroenterol 2000; 118:48-59.
41)
Kidd M, Tang LH,
MODLIN IM, Zhang T, Chin K, Holt PR, Moss S. Gastrin-Mediated
Alterations in Gastric Epithelial Apoptosis and Proliferation in a
Mastomys Rodent Model of Gastric Neoplasia. Digestion
2000:62:143-151.
42)
Kidd M, Tang LH, Schmid S,
Lauffer J, Louw JA, MODLIN IM.
Helicobacter pylori
Lipopolysaccharide Alters ECL Cell DNA Synthesis via a CD 14 Receptor and
Polyamine Pathway in Mastomys. Digestion 2000:62:217-224.
43)
Miu K, Sun L, Tang LH,
MODLIN IM. Influence of Helicobacter pylori lipopolysaccharide on the
function of enterochromaffin-like cells in vitro. Zhonghua Nei Ke Za Zhi
1999; 38:670-672.
44)
Kolby L, Wangberg B, Ahlman H,
MODLIN IM, Theodorsson E, Nilsson O. Altered influence of
CCK-B/gastrin receptors on HDC expression in ECL cells after neoplastic
transformation. Regul Pept 1999; 85:115-123.
45)
Lauffer JM, MODLIN IM,
Tang LH. Biological relevance of pituitary adenylate cyclase-activating
polypeptide (PACAP) in the gastrointestinal tract. Regul Pept 1999; 84:1-12.
46)
MODLIN IM, Tang LH. Cell and tumor biology of the gastric
enterochromaffin-like cell. Ital J Gastroenterol Hepatol 1999; 31 Suppl
2:S117-30.
47)
Schmid SW,
MODLIN IM, Tang LH, Stoch A, Rhee S, Nathanson MH, Scheele GA,
Gorelick FS. Telenzipine-sensitive muscarinic receptors on rat pancreatic
acinar cells. Am J Physiol 1998; 274:G734-G741
48)
MODLIN IM,
Poulsom R. Trefoil peptides: mitogens, motogens or mirages? Clin
Gastroenterol 1997; 25 Suppl 1:S94-100
49)
John KD, Ballantyne GH,
MODLIN IM. Octreotide acetate
inhibits motility in the rabbit distal colon. Eur Sur Res 1997; 29:311-8
50)
Kidd M, Miu K, Tang LH,
Perez-Perez GI, Blaser MJ, Sandor A,
MODLIN IM. Helicobacter pylori lipopolysaccharide stimulates histamine
release and DNA synthesis in rat enterochromaffin-like cells.
Gastroenterology 1997; 113:1110-7
51)
Tang LH, Luque EA, Efstathiou JA, Bortecen KH, Kidd M,
Tarasova NI, MODLIN IM.
Gastrin receptor expression and function during
rapid transformation of the enterochromaffin-like cells in an African
rodent. Regul Pept. 1997; 72:9-18
52)
Tsunoda Y,
MODLIN IM. Signal Transduction machinery of the Parietal Cell
Secretory System. Biomedical Research 1997, 17: 403-428
53)
Kolby L, Wangberg B, Ahlman H,
MODLIN IM, Granerus G,
Theodorsson E, Nilsson O. Histidine decarboxylase expression and histamine
metabolism in gastric oxyntic mucosa during hypergastrinemia and carcinoid
formation. Endocrinology 1996; 137: 4435-42
54)
Wangberg B, Nilsson O,
Theodorsson E, MOLDIN IM,
Dahlstrom A, Ahlman H. The effect of vagotomy on enterochromaffin-like cells
in the mastomys natalensis. J. Autonomic Nervous System 1996; 59:133-9
55)
MODLIN IM,
Zhu ZH, Tang LH, Kidd M,
56)
Borin JF, Tang LH, Kidd M, Kiu
K, Bortecen KH, Sandor A, MODLIN IM.
Somatostatin receptor regulation of gastric enterochromaffin-like cell
transformation to gastric carcinoid. Surgery 1996, 120: 1026-32
57)
Tang LH,
MODLIN IM,
58)
MODLIN IM,
Tang LH. The Enterochromaffin-like cell: An Enigmatic Cellular Lesion (ECL).
Gastroenterol 1996, 111: 783-810
59)
Kidd M, Tang LH, Miu K,
60)
Tang LH,
MODLIN IM. Somatostatin Receptor Regulation of Gastric Carcinoid
Tumors. Digestion 1996, 57 (Suppl 1): 11-14.
61)
Goldenring JR, Ray GS, Soroka
CJ, Smith J, MODLIN IM, Meise K,
Coffey RJ. Over-Expression of Transforming Growth Factor- a Alters the
Differentiation of Gastric Cell Lineages. Dig Dis Sci 1996, 41 (4): 773-784.
62)
Longley BJ, Tyrrell L, Lu SZ,
Ma Y-S, Langley K, Ding T-G, Duffy T, Jacobs P and
MODLIN IM. Somatic c-KIT
Activating Mutation in Uticaria Pigmentosa and Aggressive Mastocytosis;
Establishement of Clonality in a Human Mast Cell Neoplasm. Nature Genetics
1996; 12 (3):312-314.
63)
MODLIN IM,
64)
Sandor A, Kidd M,
65)
Tang LH, Goldenring JR,
Caufield T, MODLIN IM. A Novel
Serine Kinase Activity Associated with Exocrine Secretory Granule Membranes.
Am J Physiol 1995; 269: G481-489.
66)
Geibel J, Abraham R,
MODLIN IM, Sachs G. Gastrin
Stimulation of Changes in Intracellular Ca2+ in Parietal
Cells Depends on Levels of cAMP. Gastroenterology, 1995; 109:1060-1067.
67)
Powers RE,
68)
Delle Fave G, Helander H, Holt
S, MODLIN IM, Powers R, Solcia E,
Soll A, Tielemans, Wright NA. Acid Suppression and Gastric Mucosal Cell
Biology. Dig Dis Sci 1995; Vol. 40 (2):121S-131S.
69)
Wängberg B, Nilsson O,
Theodorsson E, MODLIN IM,
Dalhström A, Ahlman H. Are Enterochromaffin Like Cell Tumours Reversible? An
Experimental Study on Gastric Carcinoids Induced in Mastomys by Histamine
2-Receptor Blockade. J Regul Pept 1995; 56, 19-33.
70)
Quin JA, Sgambati SA,
Goldenring JR, Basson MD, Fielding LP,
MODLIN IM, Ballantyne GH. PYY
Inhibition of VIP-Stimulated Ion Transport in the Rabbit Distal Ileum. J
Surg Res 1995; 58, 111-115.
71)
72)
Delle Fave G, Helander H, Holt
S, MODLIN IM, Powers R, Solcia E,
Soll A, Tielemans, Wright NA. Acid Suppression and Gastric Mucosal Cell
Biology. Dig Dis Sci 1994 39 (9):1843-1852.
73)
MODLIN IM,
74)
MODLIN IM,
Geibel J, Tang LH, Goldenring J. Characterization of Parietal Cell Confocal
Microscopy. In: Molecular and Cellular Mechanisms of H+ Transport. Ed. B
Hirst. Nato ASI Series H: Cell Biology Vol. 89: 329-340. Springer Verlag
1994.
75)
Boron WF, Waisbren SJ,
MODLIN IM, Geibel JP. Unique
Permeability Barrier of the Apical Surface of Parietal and Chief Cells in
Isolated Perfused Gastric Glands. J Exp Biol 1994; 196 247-360.
76)
Goldenring JR, Soroka CJ, Shen
KR, Tang LH, Rodriguez W, Vaughn HD, Stoch SA,
MODLIN IM. Enrichment of rab11, a
small GTP-binding protein, in gastric parietal cells. Am J Physiol 267
(Gastrointest. Liver Physiol. 30):G187-G194; 1994.
77)
Basson MD, Beidler DR,
Turowski G, Zarif A, MODLIN IM,
Jena BP, Madri JA. Effect of Tyrosine Kinase Inhibition on Basal and
Epidermal Growth Factor-Stimulated Human Caco-2 Enterocyte Sheet Migration
and Proliferation. J Cell Physiol 160:491-501; 1994.
78)
MODLIN, IM,
Kumar RR, Soroka CJ, Ahlman H, Nilsson O. Goldenring JR. Histamine as an
Intermediate Growth Factor in Genesis of Gastric ECLomas Associated with
Hypergastrinemia in Mastomys. Dig Dis Sci,1994; 39: (7):1446-1453.
79)
Waisbren SJ, Geibel J, Boron
WF, MODLIN IM. Luminal perfusion
of isolated gastric glands. Am J Physiol 266 (Cell Physiol.35): C1013-C1027,
1994.
80)
Waisbren S, Geibel J,
MODLIN IM, Boron W. Unusual
Permeability Properties of Gastric Gland Cells. Nature 1994;
368(6469):332-335.
81)
Frankel WL, Zhang W, Singh A,
Klurfeld DM, Don S, Sakata T, MODLIN
IM, Rombeau JL. Mediation of the Trophic Effects of Short-Chain Fatty
Acids on the Rat Jejunum and
82)
Ballantyne GH, Goldenring JR,
Fleming FX, Rush S,
83)
Tsunoda Y,
MODLIN IM, Tyrosine kinase activities in the modulation of
stimulated parietal cell secretion. Am J Physiol, 1993; 264:G351-G356.
84)
Chough SP, Goldenring JR,
85)
Basson MD,
MODLIN IM, Turowski G, Madri JA. Enterocyte-matrix interactions in
the healing of mucosal injury. Eur J Gastroenterol & Hepatology 1993, 5
(suppl 3):S21-S28.
86)
MODLIN IM,
Basson MD, Soroka CJ, Wright NA, Poulsom R, Chinnery R, Hanby A, Patel K,
Rogers L, Alison M. Ulcer-induced alterations in cell phenotype and matrix
and growth factor expression. European Jo of Gastroenterology & Hepatology
1993, 5 (suppl 3):S59-S67.
87)
Tang LH, Miller MD, Goldenring
JR, MODLIN IM, Hersey SJ. Partial
agonism by gastrin for a cholecystokinin receptor mediating pepsinogen
secretion. Am J Physiol. 265 (Gastrointest. Liver Physio. 28): G865-G872,
1993.
88)
MODLIN IM,
Tang LH,
89)
Goldenring JR, Shen RK,
Vaughan JD, MODLIN
IM. Identification of a Small GTP-binding Protein, Rab25, Expressed
in the Gastrointestinal Mucosa, Kidney, and Lung. J Biological Chem l993;
268:18419-18422.
90)
91)
Ballantyne GH, Goldenring JR,
92)
MODLIN IM,
Tang LH. A new look at an old hormone - gastrin. Elsevier Science
Publishing. TEM 1993; 4:2.
93)
Nilsson B, Wängberg L,
Johansson E, Theodorsson E, Dahlstrom A,
MODLIN IM, Ahlman H. Development
of gastric carcinoids in mastomys during histamine2-receptor blockade. Agents Actions 38, Special
Conference Issue 1993.
94)
Nilsson O, Wangberg B,
Johansson L, Theodorsson E, Dahlstrom A,
MODLIN IM, Ahlman H. Rapid
induction of enterochromaffinlike cell tumors by Histamine2
receptor blockade. Am J Pathol 1993; 142:1173-1185.
95)
96)
Characterization of membrane
and cytoskeletal compartments in cultured parietal cells: Immunofluorescence
and confocal microscopic examination. Eur J Cell Biol 1993; Feb.
97)
Young GO, Stemmet N, Lastovica
A, van der Merwe EL, Louw JA, MODLIN
IM. Helicobacter pylori lipopolysaccharide stimulates gastric mucosal
pepsinogen secretion. Aliment. Pharmacol. Ther. (1992) 6:169-177.
98)
Tsunoda Y, Funasaka M,
MODLIN IM, Hidaka H, Fox L,
Goldenring J. An inhibitor of Ca2+/calmodulin-dependent protein kinase II, KN-62, inhibits
cholingergic-stimulated parietal cell secretion. Am J Physiol 1992;
262(25):G118-G122.
99)
Goldenring JR, Asher VA,
Barreuther MF, Lewis JJ, Lohmann SM, Walter U,
MODLIN IM. Dephosphorylation of
cAMP-dependant protein kinase regulatory subunit in stimulated parietal
cells. Am J Physiol 1992; 25(4):G763-G773.
100)
Armstrong DN, Ballantyne GH,
MODLIN IM. Erythromycin
stimulates ileal motility by activation of dihydropyridine-sensitive calcium
channels. J Surg Research 1992; 52:140-146.
101)
Goldenring JR, Tsunoda Y,
Stoch SA, Coffey RJ, MODLIN IM.
Transforming growth factor-alpha (TGFa) inhibition of parietal cell
secretion: structural requirements for activity. Reg Pep 1992;
43(1-2):37-47.
102)
Funasaka M, Fox LM, Tang LH,
MODLIN IM, Goldenring J. the
major calmodulin-binding protein in rabbit parietal cells is CA2+/Calmodulin-dependent
protein kinase II. Biochem Internat 1992; 27(6):1101-1109.
103)
Frankel W, Zhang W, Singh A,
Klurfeld D, Sakata T, MODLIN IM,
Rombeau J. Stimulation of the autonomic nervous system (ans) mediates
short-chain fatty acid (SCFA) - induced jejunal trophism. Surg Forum 1992;
43:24-25.
104)
Tang LH, Stoch SA,
MODLIN IM, Goldenring JR. Identification of rab2 as a
tubulovesicle-membrane associated protein in rabbit parietal cells.
Biochem J 1992; 285:715-719.
105)
Basson MD,
MODLIN IM, Madri JA. Human enterocyte (Caco-2) migration is
modulated in vitro by extracellular matrix composition and epidermal growth
factor. J Clin Invest 1992; 90(1):15-23.
106)
MODLIN IM,
Kumar R, Nangia A, Soroka CJ, Pasikhov D, Goldenring JR. Gastrin-dependent
inhibitory effects of octreotide on the genesis of gastric ECLomas. Surgery
1992; 112(6):1048-1058.
107)
Dempsey PJ, Goldenring JR,
Soroka CJ, MODLIN IM, McClure RW,
Lind CD, Ahlquist DA, Pittelkow MR, Lee DC, Sandgren EP, Page DL, Coffey RJ.
Possible role of transforming growth factor a in the pathogenesis of
Ménétrier's Disease: Supportive Evidence from Humans and Transgenic Mice.
Gastroenterology 1992;103(6):1950-1963.
108)
Reubi JC, Waser B, Horisberger
U, Halter F, Soroka CJ, Kumar RR, Goldenring JR,
MODLIN IM. Identification of somatostatin and gastrin receptors on
enterochromaffin-like cells from Mastomys gastric tumors. Endocrinology
1992; 131(1):166-172.
109)
Grady T,
110)
MODLIN, IM,
111)
Goldenring JR, Tang LH,
MODLIN IM. Small GTP-Binding
Proteins in Parietal Cells: Candidate Modulators of Parietal Cell Membrane
Dynamics. Yale J Biol and Med 1992; 65(6):597-605.
112)
Gorelick FS,
MODLIN IM,
113)
Vukasin AP, Ballantyne GH,
MODLIN IM, Nilsson O, Bilchik AJ,
Pernikoff BJ, Blair RM, Adrian TE. Plasma and tissue alterations of peptide
YY and enteroglucagon in rats after colectomy. Yale J Biol and Med 1992;
65(1):1-15.
114)
Basson MD,
MODLIN IM,
115)
Basson MD, Goldenring JR, Tang
LH, Lewis JJ, Padfield P, Jamieson J,
MODLIN IM. Redistribution of 23 kDa tubulovesicle-associated GTP-binding
proteins during parietal cell stimulation. Biochem J 1991; 279:43-48.
116)
Leach SE,
MODLIN IM,
117)
Longo WE, Ballantyne GH,
118)
Armstrong DA, Ballantyne GH,
Adrian TE, Bilchik AJ, McMillen MA,
MODLIN IM. Adaptive increase in Peptide YY and enteroglucagon after
proctocolectomy and pelvic ileal reservoic construction. Dis
119)
MODLIN IM,
Esterline W, Kim H, Goldenring JR. Enterochromaffin-like cells and gastric
argyophil carcinoidosis. Acta Oncologica 1991; 30:493-498.
120)
Nilsson O, Bilchik AJ,
Goldenring JR, Ballantyne GH, Adrian TE,
MODLIN IM. Distribution and
immunocytochemical colocalization of peptide YY and enteroglucagon in
endocrine cells of the rabbit colon. Endrocrinology 1991;
129(1):139-148.
121)
Armstrong DN, Ballantyne GH,
MODLIN IM. Peptide YY (PYY) and
neuropeptide Y (NPY) reverse VIP inhibition of motility in isolated perfused
rabbit ileum. Surgical Forum 1991; 42.
122)
Neville R, Fielding LP,
123)
124)
125)
126)
MODLIN IM,
Basson MD, Adrian TE, Sussman J. Pepsinogen release and acid secretion from
human and guinea pig gastric mucosa compromised by hypoxia, endotoxin or
critical illness. Scand J Gastro 1990; 25(9):861-875.
127)
128)
Basson MD,
129)
MODLIN IM,
Bilchik AJ, Nilsson O, Goldenring JR. Enterochromaffin-like cell tumor
induction in mastomys by insurmountable H2-receptor blockade. Research &
Clin Forums 1990;
130)
Lewis J, Goldenring J, Asher
V, MODLIN IM. The effects of
epidermal growth factor (EGF) on signal transduction in rabbit parietal
cells. Am J Physio 1990; 258(3 part 1):G476-G483.
131)
Lewis J, Goldenring J,
MODLIN IM, Coffey R. Inhibition
of parietal cell H+ secretion by transforming growth factor alpha: A
possible autocrine regulatory mechanism. Surgery 1990; 108(2):220-227.
132)
McMillen M,
133)
Nilsson O, Bilchik AJ,
134)
Bilchik AJ, Zucker KA, Adrian
TE, Sussman J, MODLIN IM. Effects
of a specific cholecystokinin receptor antagonist in a traumatic model of
pancreatitis. Surg Res Comm 1990; 8(1):47 - 57.
135)
Bilchik AJ, Nilsson O,
MODLIN IM, Zucker KA,
136)
Bilchik AJ, Zucker KA, Adrian
TE, MODLIN IM. Amelioration of
cholinergic-induced pancreatitis with a selective cholecystokinin receptor
antagonist. Arch Surg Dec 1990; 125:1546-1549.
137)
138)
Ballantyne GH, Longo WE,
Savoca PE, Adrian TE, Vukasin AP, Bilchik AJ, Sussman J,
MODLIN IM. Deoxycholate-stimulated release of peptide YY from the
isolated perfused rabbit left colon. Am J Physiol 1989; 257(5 pt 1):
G715-G724.
139)
Fleming FX, Ballantyne GH,
Goldenring JP, Fielding LP, MODLIN IM.
Paracrine modulation of vasoactive intestinal peptide (VIP) stimulated ion
transport by peptide YY in the rabbit distal colon. Surgical Forum 1989;
40:184-186.
140)
Bean AJ, Adrian TE,
MODLIN IM, Roth RH. Dopamine and
neurotensin storage in colocalized and non-colocalized neuronal populations.
J Pharm & Exp Ther 1989; 249(3):681-687.
141)
Adrian TE, Goldenring JR,
Oddsdottir M, Zdon MJ, Zucker KA, Lewis JJ,
MODLIN IM. A micro-method for the
assay of cellular secretory physiology: Application to rabbit parietal
cells. Anal Biochem 1989; 182(2):346-352.
142)
Zdon MJ, Lewis JJ,
143)
Zucker KA, Bilchik AJ,
MODLIN IM, Adrian TE.
Prostaglandin E analogue inhibition of pancreatic enzyme secretion. Pancreas
1989; 4 (6):708-714.
144)
Zdon MJ, Lewis JJ,
145)
Bilchik AJ, Nilsson O,
MODLIN IM, Sussman J, Zucker KA,
Adrian TE. H2-receptor
blockade induces peptide YY and enteroglucagon-secreting gastric carcinoids
in mastomys. Surgery 1989; 106:1119-27.
146)
Zucker KA, Adrian TE, Bilchik
AJ, MODLIN IM. Effects of the CCK
receptor antagonist L364,718 on pancreatic growth in adult and developing
animals. Am J Physiol 1989; 257(4 pt 1):G511-G516.
147)
MODLIN IM,
Bilchik AJ, Zucker KA, Adrian TE, Sussman J, Graham SM. Cholecystokinin
augmentation of 'surgical' pancreatitis. Benefits of receptor blockade. Arch
Surg 1989; 124(5):574-578.
148)
Lewis JJ, Goldenring JR,
149)
McMillen MA, Schaefer HC,
MacArthur JD,
150)
151)
Ballantyne GH, Zdon MJ, Zucker
KA, MODLIN IM. cAMP and calcium
mediated modulation of intrinsic factor secretion in isolated rabbit gastric
glands. J Surg Res 1989; 46:241-245.
152)
Basson MD, Fielding L, Bilchik
AJ, Zucker KA, Ballantyne GH, Sussman J,
153)
Longo WE, Ballantyne GH,
Vukasin AP, Bilchik AJ,
154)
Zucker KA, Adrian TE,
MODLIN IM. Current Research
Review. Cholecystokinin receptor antagonists. J Surg Res 1988; 45:496-504.
155)
Zucker KA, Adrian TE,
Ballantyne GH, MODLIN IM.
Prostaglandin E analogue inhibition of intrinsic factor release. Scand J
Gastro 1988; 650-654.
156)
Lewis JJ, Zdon MJ,
157)
Oddsdottir M, Goldenring JR,
158)
Basson MD, Sussman J,
159)
Basson MD,
160)
Rackoff PJ, Zdon MJ, Tyshkov
M, MODLIN IM. Epidermal growth
factor (EGF) inhibits both intrinsic factor secretion and acid secretion in
histamine-stimulated isolated gastric glands. Reg Pep 1988; 21: 279-287.
161)
MODLIN IM,
Zucker KA, Zdon MJ, Sussman J,
162)
163)
Basson MD, Zucker KA, Adrian
TE, Zdon MJ, Ballantyne GH, MODLIN IM.
Pepsin release by prostaglandin E1 analogue: A potential
therapeutic problem. Arch Surg 1988; 123(4): 431-433.
164)
Ballantyne GH, Esterline WJ,
Zdon MJ, Zucker KA, Adrian TE, MODLIN
IM. Histamine stimulated acid secretion in the isolated perfused porcine
stomach: An in vitro model of acid secretion. Surg Res Comm 1988; 3:199-206.
165)
Basson MD,
MODLIN IM. Current Research Review: Pepsinogen: Biological and
pathophysiologic significance. J Surg Res 1988; 44: 82-97.
166)
Goldenring JR, Oddsdottir M,
MODLIN IM. A novel protein kinase
activity in rabbit gastric gland cytosol. Biochem Biophys Res Commun 1987;
142: 559-566.
167)
MODLIN IM,
Schafer DE, Ballantyne GH, Fratesi GR, Tyshkov M, Zdon MJ. Isolated gastric
glands in the study of gastric secretory relationships. Surg Res Comm 1987;
1(2):81-96.
168)
Zucker KA, Zdon MJ, Adrian TE,
Ballantyne GH, MODLIN IM.
Prostaglandin inhibition of acid is cAMP dependent. J Surg Res 1987;
42:513-520.
169)
Zucker KA, Adrian TE, Sussman JE,
MODLIN IM.
New potent cholecystokinin
antagonists block cerulein-induced pancreatitis. Surg Forum 1987;
38:142-144.
170)
Zucker KA, Adrian TE, Zdon MJ,
Ballantyne GH, MODLIN IM.
Asperlicin: A unique non-peptide cholecystokinin antagonist. Surgery 1987;
102(2):163-170.
171)
Zdon MJ,
MODLIN IM, Ballantyne GH, Zucker KA, Rackoff P. Proton pump
inhibition as evidence for separate intracellular mechanisms of acid and
intrinsic factor secretions. Surg Res Commun 1987; 1(4):293-302.
172)
Zdon MJ, Zucker KA, Adrian TE,
MODLIN IM. Somatostatin analogue
inhibition of isolated parietal cell secretion. Surgery 1987; 102:967-973.
173)
Oddsdottir M,
MODLIN IM, Zucker KA, Zdon MJ, Goldenring JR. A Calmodulin-dependent
kinase in parietal cells. Biochem Biophys Res Commun 1987; 148:1390-1397.
174)
MODLIN IM,
Oddsdottir M,
175)
176)
Basson MD,
177)
Oddsdottir M, Ballantyne GH,
Adrian TE, Zdon MJ, Zucker KA, MODLIN
IM. Somatostatin inhibition of intrinsic factor secretion from isolated
guinea pig gastric glands. Scand J Gastroenterol 1987; 22:233-238.
178)
Ballantyne GH, Zdon MJ, Schafer DE, Fratesi GR, Roberts
JR, Tyshkov M, MODLIN IM.
Evidence for dual modulation of pepsinogen
secretion using Isoproterenol, Carbachol, CCK-8, Forskolin, 8 Bromo-cAMP,
and A23187 probes. Ann Surg 1986, 204(5):559-565.
179)
Goldenring JR,
MODLIN IM, Tyshkov M, Zdon MJ, Schafer DE, Ballantyne GH. A
manganese-dependent protein kinase in gastric gland cytosol. Surgery 1986;
100(2):181-187.
180)
Oddsdottir M, Goldenring JR,
Tyshkov M, Zucker KA, Zdon MJ, MODLIN
IM. Characterization of a parietal cell cytosolic calmodulin-dependent
kinase system. Surg Forum 1986; 37:177-179.
181)
Ballantyne GH, Zdon MJ, Zucker
KA, Tyshkov M, Fratesi GR, Schafer DE,
MODLIN IM. Vasoactive intestinal
peptide (VIP) augments cholecystokinin-8- (CCK-8) stimulated pepsinogen
secretion: Evidence for dual modulation of chief cell function. J Surg Res
1986; 40(6):617-623.
182)
MODLIN IM,
Fratesi GR, Schafer DE, Zdon MJ, Ballantyne GH, Tyshkov M. Paradoxical
effect of trifluoperazine, a calmodulin antagonist, on pepsinogen secretion.
J Surg Res 1986; 40(6):624-631.
183)
Zdon MJ, Ballantyne GH,
Schafer DE, Tyshkov M,
184)
Zdon MJ, Ballantyne GH,
Schafer DE, Tyshkov M,
185)
MODLIN IM, Schafer DE, Tyshkov M,
Ballantyne GH, Fratesi GR, Roberts JR, Zdon MJ.
Forskolin-dependent (cyclic adenosine monophosphate) protein phosphorylation
in isolated gastric glands. Arch Surg 1986; 121(3):330-337.
186)
Fratesi GR, Zdon MJ, Ballantyne GH, Schafer DE, Roberts
JR, Tyshkov M, MODLIN IM.
Isolated gastric glands: An in-vitro model of
gastric secretion. Curr Surg 1986; 43(3):205-207.
187)
Ballantyne GH, Zdon MJ, Schafer DE, Fratesi GR, Roberts
JR, Tyshkov M, MODLIN IM.
Evidence for dual modulation of pepsinogen
secretion using isoproterenol, carbachol, CCK-8, Forskolin, 8 Bromo-cAMP and
A23187 probes. Ann Surg 1986; 204(5):559-565.
188)
Ballantyne GH,
MODLIN IM, Zdon MJ, Tyshkov M, Fratesi GR, Schafer DE.
Intracellular modulation of parietal cell
macromolecular secretion. Surg Forum 1985; 36:128-130.
189)
Zdon MJ, Ballantyne GH, Schafer DE, Fratesi GR, Roberts
JR, Tyshkov M, MODLIN IM.
The effects of cholecystokinin on parietal cell
secretion in isolated gastric glands. Surgery 1985; 98(6):1038-1044.
190)
MODLIN IM,
Albert DL, Crochelt R, Sank A, Materia A, Jaffe BM. Bombesin and insulin
stimulated pancreatic polypeptide release as a discriminator of vagal
integrity. Surg Gynecol Obstet 1983 Jun; 156(6):729-736.
191)
Valenzuela JE, Lamers CB,
MODLIN IM, Walsh JH. Cholinergic
component in the human pancreatic secretory response to intraintestinal
oleate. Gut 1983; 24(9): 807-811.
192)
Weber C,
MODLIN IM, DiBella F, LoGerfo P, Hardy M, Feind C, Reemtsma K.
Pancreatic polypeptide (PP) immunoreactivity in human parathyroid culture
media. J Surg Res 1983; 35(5): 21-425.
193)
MODLIN IM,
Jaffe BM, Albert D, Sank A, Materia A, Crochelt R. Cholinergic stimulation
of pancreatic polypeptide release by a meal, bombesin, neurotensin,
tetragastrin, cholecystokinin and cerulein. J Surg Res 1983; 35(2):113-118.
194)
Mitchell JJ,
MODLIN IM, D`Sa AA, Barros SR, Bloom SR. Pharmacokinetics of VIP in
dog and pig. Experientia 1982; 38(9):1091-1093.
195)
Materia A, Jaffe BM,
MODLIN IM, Sank A, Albert D.
Effect of methionine-enkephalin and naloxone on bombesin-stimulated gastric
acid secretion, gastrin, and pancreatic polypeptide release in the dog. Ann
Surg 1982; 196(1):48-52.
196)
Materia A,
MODLIN IM, Sank AC, Albert D, Jaffe BM. Opiate modulation of
pancreatic polypeptide release by a meal in the dog. J Pharmacol Exp Ther
1982; 223(2):355-358.
197)
Zinner MJ, Kasher F,
MODLIN IM, Jaffe BM. Effect of
xenopsin on regional blood flow, hormone release and gastric acid secretion.
Am J Physiol 1982; 243(3): G195-G199.
198)
Jaffe BM, Akande B,
MODLIN IM, Albert D, Reilly P.
Cholinergic modulation of substance P release. Dig Dis Sci 1982 Jan; 27(1):
28-32.
199)
Sank AC,
MODLIN IM, Jaffe BM, Albert DL, Crochelt R. Unreliability of
bombesin as a diagnostic test for retained antrum. Surg Forum 1981; 32:
214-216.
200)
MODLIN IM,
Albert DL, Crochelt R, Sank AC, Materia A, Jaffe BM. Bombesin and insulin
stimulated pancreatic polypeptide release as a discriminator of vagal
integrity. Surg Forum 1981; 32:211-214.
201)
Albert DL, Koenig M, Crochelt
R, Sank A, Materia A, MODLIN IM,
Andersen DK. Enhancement of sensitivity to insulin by pancreatic resection.
Surg Forum 1981; 32:205-207.
202)
MODLIN IM,
Albert D, Crochelt R, Sank A, Jaffe BM. Evidence for an intestinal mechanism
of pancreatic polypeptide release. Dig Dis Sci 1981; 26(7):587-590.
203)
MODLIN IM,
Albert D, Sank A, Materia A, Crochelt R, Jaffe BM. Role of the antrum in the
modulation of plasma pancreatic polypeptide levels. J Surg Res 1981;
30(3):269-275.
204)
Materia A,
MODLIN IM, Albert D, Sank A, Crochelt RF, Jaffe BM. Effect of
somatostatin and 16,16-Dimethyl-prostaglandin E2 on
bombesin-stimulated canine gastric acid, plasma gastrin and pancreatic
polypeptide secretion. Regul Pep 1981; 1(4): 297-305.
205)
MODLIN IM,
Lamers CBH, Walsh JH. Stimulation of canine pancreatic polypeptide, gastrin
and gastric acid secretion by ranatensin, litorin, bombesin nonapeptide and
substance P. Regul Pept 1981; 1(4):279-288.
206)
MODLIN IM,
Ehrlich BE, Lamers CBH, Diamond JM, Walsh JH. Variable effect of lithium on
canine pancreatic polypeptide and gastrin release by a meal or bombesin.
Digestion 1981; 22(4):177-184.
207)
MODLIN IM,
Albert D, Sank A. Current aspects of gut hormones. J Surg Res 1981;
30(6):602-618.
208)
Varner AA,
MODLIN IM, Walsh JH. High potency of bombesin for stimulation of
human gastrin release and gastric acid secretion. Regul Pept 1981;
1(4):289-296.
209)
MODLIN IM,
Lamers CHB, Walsh JH, Jaffe BM. Bombesin - a vagally independent stimulator
of gastrin release. Am J Surg 1981; 141(1): 98-104.
210)
Akande B, Reilly P,
MODLIN IM, Jaffe BM: RIA
measurement of Substance P following a meat meal. Surgery 1981; 89(3):
378-383.
211)
MODLIN IM,
Lane FC, Albert D, Sank A, Crochelt R, Beyer M, Jaffe BM. Failure of
pancreatic polypeptide release by pancreatic transplants. Surg Forum 1980;
31:209-210.
212)
Morley JE, Varner A,
MODLIN IM, Carlson HE, Braunstein
GD, Walsh JH, Herschman JM. Failure of bombesin to alter anterior pituitary
hormone secretion in man. Clin Endocrinol 1980; 13(4):369-373.
213)
MODLIN IM,
Lamers CBH, Jaffe BM. Evidence for cholinergic dependence of pancreatic
polypeptide (PP) release by bombesin - a possible application. Surgery 1980;
88(1):75-85.
214)
MODLIN IM,
Jaffe BM. The clinical usefulness of glucagon. Surgery 1980; 87(4):470-472.
215)
MODLIN IM,
Lamers CBH, Walsh JH. Mechanisms of gastrin release by bombesin and food. J
Surg Res 1980; 28(6): 539-546.
216)
217)
MODLIN IM,
Lamers C, Shulkes A, Walsh JH. Release of vasoactive intestinal polypeptide
(VIP) from the pancreas. Surg Forum 1979; 30:405-407.
218)
MODLIN IM,
Bloom SR. VIP and the WDHA syndrome. Gastroenterology 1979; 76(5):1078-1079.
219)
220)
MODLIN IM,
Hansky J, Singer M, Walsh JH. Evidence that the cholinergic enteropancreatic
reflex may be independent of cholecystokinin release. Surgery 1979;
86(2):352-361.
221)
Christofides N,
MODLIN IM, Sarsin D, Adrian T, Bloom SR. The release of gastrin, PP,
VIP, and motilin after an oral water load and atropine in man. Clin Sci Mol
Med 1978; 75(6):1051-1054.
222)
MODLIN IM,
Mitchell SJ, Bloom SR. Experimental evidence for vasoactive intestinal
peptide as the cause of the watery diarrhea syndrome. Gastroenterology 1978;
75(6):1051-1054.
223)
MODLIN IM
Mitchell S, Bloom SR. Plasma vasoactive intestinal polypeptide (VIP) levels
and intestinal ischaemia. Experientia 1978; 34(4): 535-536.
224)
MODLIN IM,Bloom
SR, Mitznegg P. Motilin release in the pig. Gut 1978; 19(5): 399-402.
225)
Bryant MG, Polak JM,
MODLIN IM, Bloom SR, Albuquerque
RH, Pearse AG. Possible dual role for vasoactive intestinal peptide as a
gastrointestinal hormone and neurotransmitter substance. Lancet 1976 May;
1(7967):991-993.
C. Historical Articles
1)
Drozdov I,
MODLIN IM, Kidd M, Golubinov VV. Nikolai Konstantinovich Kulchitsky (1865-1925). J
Med Biography 2009; 17(1):47-54.
2)
Drozdov I, MODLIN IM, Kidd M,
Golubinov VV. From Leningrad to London: The saga of Kulchitsky and the
legacy of the enterochromaffin cell. Neuroendocrinology 2009; 89(1):1-12.
3)
Drozdov I,
Kidd M,
MODLIN IM. Hand Amputations and the
Piano, or how diminuendo of the right hand led to fortissimo of the left. J
Hand Surgery 2008; 33:780-6.
4)
Malfertheiner MV, Fill S, Kidd M,
MODLIN IM.
The elucidation of peptic esophagitis: From Hamperl to Heartburn.
Zeitschrift fur Gastroenterologie 2007; 45:1164-8.
5)
Kloppel G, Dege K, Remmele W, Kapran Y, Tuzlali S,
MODLIN IM. Siegfried Oberndorfer:
a tribute to his work and life between Munich, Kiel, Geneva and Istanbul.
Virch Arch 2007, Supp1:S3-7.
6)
MODLIN IM,
Kidd M, Shapiro M, Eick G. Oberndorfer and the Evolution of Carcinoid
Disease. Archives Surgery 2007; 142: 187-97.
7)
MODLIN IM,
Champaneria MC, Bornschein J, Kidd M. The evolution of the diffuse
neuroendocrine system – clear cells and cloudy origins. Neuroendocrinology
2006; 84:69-82.
8)
Champaneria M, MODLIN IM,
Kidd M, Eick G. Frederick
Feyrter: A precise intellect in a diffuse system. Neuroendocrinol 2006;
83:394-404.
9)
MODLIN IM, Sachs G, Wright NA, Kidd M.
Edkins and a Century of Acid Suppression. Digestion 2005; 72:129-145.
10)
MODLIN IM, Shapiro MD, Kidd M.
Siegfried Oberndorfer - Origins and Perspectives of Carcinoid Tumors. Human
Pathology 2004; 35:1440-51.
11)
MODLIN IM, M Kidd, K Lye. From the
Lumen to the Laparoscope. Arch Surg 2004; 139: 1110-26.
12)
MODLIN IM, Kidd M, Lye KD.
Historical perspectives on the treatment of gastroesophageal reflux disease.
Gastrointest Endosc Clin N Am. 2003 Jan;13(1):19-55, vii-viii.
13)
MODLIN IM, Kidd M, Lye KD.
Perspectives and reflections on integrated digestive surgery. Best Pract Res
Clinical Gastroenterology 2002; 16:885-914.
14)
MODLIN IM, Kidd M, Lye KD.
15)
Modlin IM, Kidd M, Hults C, Hinoue T. The surgery of chronic
pancreatitis – A chronicle of confusion and despair? World J Surg 2002;
12:1382-1396.
16)
Modlin IM, Kidd M, Hinoue T. Of Fibiger and fables:
cockroaches and Helicobacter pylori.
J Clin Gastroenterol 2001; 33:177-179.
17)
Modlin IM, Kidd M. Ernest Starling and the discovery of
secretin. J Clin Gastroenterol 2001; 32: 187-193.
18)
Kidd M,
Modlin IM. Van Swieten
and the Renaissance of the
19)
MODLIN IM, Kidd M. Ernest Starling
and the discovery of secretin. J Clin Gastroenterol 2001; 32:187-192.
20)
Modlin IM. The Quincunx of
Surgery.
21)
MODLIN IM,
Kidd M, Farhadi J. Bayliss and Starling and the nascence of endocrinology.
Reg Pep 2000; 25: 109-123.
22)
MODLIN IM,
Farhadi J. Rudolf Schindler—A Man for All Seasons. J Clin Gastroenterol,
September 2000, v. 31:(2):95-102.
23)
Kidd M,
Modlin IM. From
Bontius to Boerhaave – The
24)
Kidd M,
MODLIN IM. Frederick Ruysch - Depictor of the surreality of death. J
Med Biog 1999; 7: 69-77
25)
Kidd M,
MODLIN IM. A century of
Helicobacter pylori. Paradigms Lost - Paradigms regained. Digestion
1998; 59:1-15.
26)
MODLIN IM.
Surgical triumvirate of Theodor Kocher, Harvey Cushing and William Halsted.
World J Surg 1998; 22:103-113.
27)
MODLIN IM,
Kidd M, Sandor A. The influence of Theodor Kocher on American Surgeons.
Digestive Surgery 1997; 14:469-482.
28)
MODLIN IM,
Kidd M, Marks IN, Tang LH. The Pivotal Role of JS Edkins in the Discovery of
Gastrin. World J Surg 1997, 21: 226-234
29)
MODLIN IM.
The Surgical Legacy of Arris and Gale. Journal of Medical Biography, 1996,
4: 191-199
30)
MODLIN IM,
31)
Sandor J, Sandor A and
MODLIN IM. Eugene Pólya: The Billroth of
32)
MODLIN IM,
Basson MD. The Lester Dragstedt Centennial. J Am Coll Surg 1994, 179(1)
84-102.
33)
Begos DG,
MODLIN IM, Ballantyne GH. A Brief History of Intestinal Surgery. In:
Perspectives in
34)
MODLIN IM,
Ahlman H. Oddi: The Paradox of the Man and the Sphincter. Arch Surg,
1994;129:549-556.
35)
Waisbren SJ,
MODLIN IM. Lester R. Dragstedt and His Role in the Evolution of
Therapeutic Vagotomy in the
36)
John KD,
MODLIN IM. A Brief Historical Perspective and A Comparison Of The
Current Systems of Surgical Training in
37)
MODLIN
IM, Waisbren SJ. Pavlov in the
38)
MODLIN IM,
Shin JH. Harvey Cushing: First Guest at "The Divine Banquet of the Brayne".
Surgery 1993; 113:438-55.
39)
Waisbren SJ,
MODLIN IM. The Evolution of Therapeutic Vagotomy. Surg Gynecol &
Obstet 1990; 170:261-272.
40)
MODLIN IM.
From Prout to the proton pump - a history of the science of gastric acid
secretion and the surgery of peptic ulcer. Surg Gynecol & Obstet 1990;
170(1):81-96.
D.
Books
1)
MODLIN IM and SACHS G, Acid Related
Diseases-Biology and Treatment .Schnetzor Verlag 2004. Second Edition p1-522.
2)
MODLIN IM
and Kidd M. The Art of Dutch
Medicine,
3)
MODLIN IM and Kidd M.
Diverse and Sundry reflections on British Medicine with especial attention
to Gastroenterology: Sudler & Hennessey,
4)
MODLIN IM and Kidd M.
The Paradox of the Pancreas: from Wirsung to Whipple. Politzki Print
Productions:
5)
MODLIN IM.
The Evolution of Therapy in Gastroenterology. Sudler & Hennessey:
6)
MODLIN IM. A History of Gastroenterology at the Millenium. Milan 2000. pg 1-177.
7)
MODLIN IM. A Brief History of Endoscopy. Multi Med
8)
MODLIN IM and SACHS G, Acid Related
Diseases-Biology and Treatment .Schnetzor Verlag 1998. p1-368.
9)
MODLIN IM. The Medical legacy of
10)
MODLIN IM. The Doctors of the Dutch From
Donders to Dicke. 1998. pg 1-130.
11)
MODLIN IM. The Medici of
12)
MODLIN IM.
The Medical Vintage of
13)
MODLIN IM.
14)
MODLIN IM.
The Medical Barbers of
15)
MODLIN IM.
Tales from the
16)
MODLIN IM.
Medical milestones on the Potomac.
Schnetzor-Verlag, GmbH
17)
MODLIN IM, Ballantyne G, Lehy P. Textbook
of Laparoscopic Surgery. Lippincott. 1993.
E. Book Chapters
1)
MODLIN IM,
Gustafsson BI, Kidd M. Neuroendocrine
Tumors of the GI Tract: An appraisal of the past and perspectives for the
future in “The Oxford Textbook of Endocrinology and Diabetes” Meeran K,
Bloom S (eds) Oxford University Press (2nd edition) (in press).
2)
MODLIN IM,
Kidd M, Malfertheiner MV, Gustafsson BI.
Gastric Neuroendocrine Neoplasia
in “The Biology of Gastrointestinal Cancers” Wang TC, Fox JG, Giraud A (eds)
Springer-Verlag, NY 2008; 185-216.
3)
Oberg K, MODLIN IM.
Non-functioning pancreatic endocrine tumors in “Oberndorfer Centennial”
Modlin IM, Oberg K, (eds) (2008) p88-99.
4)
Black JW, Kidd M, MODLIN IM.
Gastrin, neoplasia and the role of
gastrin antagonists in “Oberndorfer Centennial” Modlin IM, Oberg K, (eds) (2008)
p388-97.
5)
Gustafsson BI, Kidd M, MODLIN IM.
Bronchopulmonary Carcinoid
Tumors in “Oberndorfer Centennial” Modlin IM, Oberg K, (eds) (2008)
p54-65.
6)
MODLIN IM,
Oberg K, Chung DC, Jensen RT, de Herder WW, Thakker RV, Caplin M, Delle Fave
G, Kaltsas GA, Kidd M, Krenning EP, Moss SF, Nilsson O, Rindi G, Salazar R,
Ruszniewski P, Sundin A. The Current
status of Gastroenteropancreatic Neuroendocrine Tumors in “Oberndorfer
Centennial” Modlin IM, Oberg K, (eds) (2008) p4-21.
7)
Gustafsson BI, Kidd M, Drozdov I,
MODLIN IM. The Enterochromaffin
cell in “Oberndorfer Centennial” Modlin IM, Oberg K, (eds) (2008)
p178-91.
8)
MODLIN IM,
Shapiro MD, Kidd M, Drozdov I, Gustafsson BI.
Siegfried Oberndorfer and the Origins
of Carcinoid Tumors in “Oberndorfer Centennial” Modlin IM, Oberg K,
(eds) (2008) p22-39.
9)
MODLIN IM,
Drozdov I, Gustafsson BI, Oberg K, Kidd M.
Rectal Neuroendocrine Tumors –
Diagnosis and Treatment in “Oberndorfer Centennial” Modlin IM, Oberg K,
(eds) (2008) p124-133.
10)
Gustafsson BI, Kidd M, MODLIN IM.
Small Intestinal Neuroendocrine Tumors
in “Oberndorfer Centennial” Modlin IM, Oberg K, (eds) (2008) p100-11.
11)
Kidd M, Malfertheiner M, MODLIN IM.
ECL cells: CCN2 – a clue or a
conundrum in “Oberndorder Centennial” Modlin IM (eds) (2008) p254-67.
12)
Gustafsson BI, Hauso O, Kidd M, MODLIN IM.
Carcinoid Heart Disease in
“Oberndorder Centennial” Modlin IM (eds) (2008) p298-303.
13)
MODLIN IM,
Bornschein M, Kidd M.
Gastrointestinal carcinoids
in “Gastrointestinal Oncology – A multidisciplinary approach” Jankowski JA,
Sampliner R, Kerr D, Fong Y (eds) (2007) (in press).
14)
MODLIN IM,
Kidd M,
Champaneria MC, Chan A.
Historical perspectives of surgery for pancreatic tumors in “Surgery of
Pancreatic Tumors” Shrikande SV, Buchler MW (eds) (2007)
15)
MODLIN IM,
Champaneria MC, Chan A,
Kidd M. Endocrine tumors
of the pancreas in “Surgery of Pancreatic Tumors” Shrikande SV, Buchler
MW (eds) (2007)
16)
MODLIN IM,
Latich I, Drozdov I, Bornschein J, Kidd M. Somatostatin analog therapy
in “Molecular targeting in oncology. Kaufman HL (ed) Humana Press (2008)
17)
MODLIN IM,
Champaneria MC, Chan A, Kidd M,
Eick G. The history of the
pancreas in “The Pancreas (2nd edition)” Beger HW, Buchler MW
(eds) Blackwell (2008)).
18)
MODLIN IM,
Latich I, Kidd M,
Zikusoka MN, Eick G, Champaneria MC,
Chan A. Overview of therapeutic options for Gastrointestinal carcinoids.
ASCO Educational Handbook (2007).
19)
MODLIN IM,
Kidd M,
Eick G, Latich I,
20)
MODLIN IM,
Kidd M,
Eick G, Latich I,
21)
MODLIN IM,
Zikusoka MN,
Kidd M, Latich I, Eick G,
Romanyshyn JC. The History
and Epidemiology of Neuroendocrine Tumors in “Handbook of Neuroendocrine
Tumors”, London 2006 (in press).
22)
MODLIN IM, M Kidd, K Lye.
Radio-labeled Octreotide for treatment of endocrine and other tumors in
“Progress in Oncology” DeVita VT, Jr., Hellman S, Rosenberg SA (eds). Jones
and Bartlett:
23)
MODLIN IM, K Lye, M Kidd.
Carcinoid Tumors “Endocrinologic Surgery”, Marcel Dekker, New York 2003,
Chapter 51: 611-639.
24)
Hirshowitz BI, MODLIN IM. The History of Endoscopy: The American
Perspective in “Gastroenterological Endoscopy.” Classen M, Tytgat GN,
Lightdale CJ (Eds). Thieme,
25)
Modlin IM. Hults C,
Kidd M, Hinoue T. A brief
history of chronic pancreatitis in “Chronic Pancreatitis.” Buchler MW
and Freiss H (eds).
26)
Schmid SW. Buchler MW, Kidd M,
Modlin IM.
Acute pancreatitis in
“Evidence-based Gastroenterology.” Irvine JE and Hunt RH (eds). BC Decker
Inc. Publisher,
27)
MODLIN IM,
Schmid SW, Tang LH, Farhadi J, Buchler M. Endocrine Tumors of the
Pancreas in “Pancreatic Tumors:
Achievements and Prospective.” Dervenis CG and Bassi C (Eds). Thieme,
28)
Modlin IM, Fahardi J, Kidd M.
From the pump to the Helix in “Helicobacter
pylori – Basic mechanisms to clinical cure.” Hunt RH and Tytgat GNJ
(Eds). Kluwer Academic Publishers,
29)
Schmid SW, Tang LH, Kidd M,
Modlin IM.
Muscarinic receptors on the pancreatic
acinar cell in “Acute pancreatitis: novel concepts in biology and
therapy.” Buchler MW and Uhl W (Eds).
30)
Gorelick FS,
MODLIN IM, Schmid SW. Activation of muscarinic receptors on the rat
pancreatic acinar cell is associated with cell injury. Buchler MW and Uhl W
(Eds).
31)
Schmid SW, Uhl W, Kidd M,
Modlin IM, Buchler MW.
Experimental models of acute
pancreatitis and their clinical relevance in “Acute pancreatitis: novel
concepts in biology and therapy.” Buchler MW and Uhl W (Eds).
32)
Modlin IM.
Schmidt S, M Buchler,
Management of Pancreatitis,
Evidence Based Medicine 2000
33)
Modlin IM, Kidd M, Miu K, Tang LH.
The effect of Helicobacter pylori on enterochromaffin-like (ECL) cell
function in “Helicobacter pylori
– Basic mechanisms to clinical cure.” Hunt RH and Tytgat GNJ (Eds).
Kluwer Academic Publishers,
34)
Modlin IM, Kidd M, Sandor A.
Perspectives on Stem Cells and Gut
Growth: Tales from a crypt - From the Walrus to Wittgenstein in “The Gut
as a Model in Cell and Molecular Biology.” Halter F, Winton DJ, Wright NA.
(Eds.) Kluwer Academic Publishers,
35)
MODLIN IM.
Islet Cell Neoplasia. In:
Follow-up for Cancer (4th Ed). Ed. D.S. Fischer, Lippincott - Raven,
36)
Begos DG, Lee F, Franco K,
Baldwin JC, Revkin J, MODLIN IM.
Büchler MW, Frei E, Klaiber Ch, Krähenbühl L (eds). Laparoscopic Surgery as
an Option for Gallstones in Cardiac Transplant Candidates and Recipients.
Five Years of Laparoscopic Cholecystectomy: A Reappraisal. Prog. Surg.
Basel, Karger, 1996, vol. 22 pp 118-126.
37)
Goldenring JR,
MODLIN IM. A Practical Approach to Cloning Strategies. In: Clinical
Gene Analysis and Manipulation: tools, techniques and trouble shooting, J
Jankowski, J Polak (Eds), Cambridge University Press, 1996, 270-288.
38)
MODLIN IM.
From Prout to the Proton Pump. Schnetztor-Verlag GmbH,
39)
MODLIN IM,
Rozen P, Scarpignato C. (Eds) Frontiers of Gastrointestinal Research Series.
Endocrine Tumors of the Pancreas 1995. Karger,
40)
MODLIN IM,
Begos DG, Ballantyne GH. Laparoscopic Gastrointestinal Surgery: Current
State of the Art. In: Clinical Gastroenterology (ed) H. Spiro, McGraw-Hill,
Supp 1; pp 1-20, 1994.
41)
42)
Ferzoco SJ,
MODLIN IM. Splenic Surgery. In: Laparoscopic Surgery, WB Saunders,
43)
Ballantyne GH, Leahy PF,
MODLIN IM.(eds) Laparoscopic
Surgery. WB Saunders,
44)
MODLIN IM,
Basson MD. Gall Bladder: In Current Practice of Surgery. Copeland EM, Levine
BA, Howard RJ, Sugerman H, Warshaw AL (eds). Churchill Livingstone, NY.
1993; XIII(9):3-20.
45)
DeMeester TR, Nahrwold DL,
MODLIN IM. Esophageal, gastric
and small intestine (editorial overview). In: Current Opinion in General
Surgery 1993:165-169, ed.John M. Daly, Current Science.
46)
MODLIN, IM,
Basson MD. Clinical Applications of Gastrointestinal Hormones. In
Endocrinology and Mebabolism Clinics of
47)
Soybel D,
MODLIN IM. Overview of gastric mucosal injury and inflammation: In
Gastritis. Kozol RA (ed). CRC Press,
48)
Armstrong DN, Ballantyne GH,
MODLIN IM. Ogilvie Syndrome: in
Problems in general surgery. Colorectal Disease: Challenging Problems.
Rothenberger DA (Ed) Lippincott 1992; 9(4):585-596.
49)
MODLIN, IM.
(Guest Ed) Current Clinical and Scientific Perspectives in Gastroenterology.
Yale J Biol and Med 1992; 65(5):393.
50)
51)
MODLIN IM,
Kim H, Bilchik A, Nilsson O, Esterline W, Goldenring J. Pathobiology of
enterochromaffin-like cell tumor induction in Mastomys. Fernstrom Symposium
1990. R Hakanson & F Sundler (eds) 1990; 15:499-514.
52)
MODLIN IM,
Basson M. Blood pepsinogen: Clinical and research significance: in Clinical
Investigation of Gastric Function. Fron Gastroint Res. Scarpignato C &
Bianchi Porro G (eds). Karger,
53)
MODLIN IM,
54)
MODLIN IM.
Tumor of the Endocrine Glands [Carcinoid Tumors]. Current Guidelines for the
Management of Cancer. Rene A.
Khafif, Sameer Rafla, Samuel Kopel (eds). Harcourt Brace Jovanovich,
Academic Press Inc,
55)
MODLIN IM.
Peptic ulcer syndromes - hyper and hyposecretory states: In Surg Care II. RE
Condon, JJ DeCosse (eds) Lea and Febiger,
56)
MODLIN IM.
Endocrine tumors: in Basic Principles of Surgical Oncology. Alfonso A and
Gardner B (eds).
57)
MODLIN IM,
Jaffe BM. Gastrointestinal Hormones. Endocrine Society of
58)
MODLIN IM,
Mitchell S, Bloom SR. The systemic release and pharmacokinetics of VIP. In
Gut Hormones S. Bloom (ed).
Churchill Livingstone, 1978; 470-474.
59)
MODLIN IM,
Mitchell S, Bloom SR. VIP as the cause of the WDHA syndrome. In:
Gastrointestinal Hormones and Pathology of the Digestive System. Grossman
and Speranza V (eds) Plenum Press 1978; 195-202.
Return to Publications Index
1)
MODLIN IM. George Sachs – I did it my way. J Clin Gastroenterol 2006; 40:867-9.
2)
MODLIN IM. Galen and the Properties of Foodstuffs. (Book Review) Gastroenterology.
2005 (in press).
3)
MODLIN IM. [Comments on: "Gastric
carcinoid tumours. Is there a place for antrectomy?"] Ann Chir.
2006; 131: 294.
4)
MODLIN IM, Adler G, Alexander K, Arnold R,
Brenner DA, Corazziari E, Floch MH, Laporte RE, Peterson WL, Quigley EM,
Shapiro MD, Spechler SJ, Spiller RC, Tytgat GN, Wiegers W. Information
assimilation and distribution challenges and goals for real and virtual
journals. J Clin Gastroenterol 2005; 39: 181-8.
5)
MODLIN IM. (Foreword) Best
Pract Clin Gastroenterol, 2004; 18 Suppl: 1-6.
6)
MODLIN IM. (Foreword) History
of Helicobacter pylori by Barry Marshall, 2003.
7)
MODLIN IM. (book review)
Clinical Endocrinology and Metabolism: The Gut as an Endocrine Organ. Eds. P.
Fuller and A Schulkes, Gastroenterol, 1994.
8)
MODLIN IM. (book review)
The Gastrointestinal Surgical Patient: Preoperative and Postoperative Care.
Eds. EMM Quigley and MF Sorrell, Williams & Wilkins, Baltimore, 1994.
9)
MODLIN IM.
(book review) Horace W. Davenport. A History of Gastric Secretion and
Digestion: Experimental Studies to 1975. Jo of the History of Med: Vol 48,
October, 1993.
10)
MODLIN IM,
Sabesin SM, Snape WJ Jr., Rubin W. Manpower in gastroenterology in the United
States: A position paper of the training and education committee of the AGA.
Gastroenterology 1989; 96(3):956-958.
11)
Zdon MJ, Lewis
JJ,
12)
Rikkers LF,
Bland KI, Kinder BK, Lawrence PF, Lynch TG,
MODLIN IM, Schulak JA, and Whitehouse WM Jr. Funding of surgical research:
the roles of government and industry. J Surg Res 1985; 39(3):209-215.
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to Publications Index
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